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CCs - Haematological > CCs - in brief > Flashcards

CCs - in brief Flashcards

1
Q

What are lymphomas?

A

Disorders caused by malignant proliferation of lymphocytes
These accumulate in the lymph nodes, peripheral blood or organs
Hodgkin’s and non-Hodkin’s

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2
Q

What is the difference between Hodgkin’s and non-Hodgkin’s?

A

In Hodgkin’s, Reed-Sternberg cells (mirror-image nuclei) are found
RS cells are derived from B-lymphocytes

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3
Q

How does Hodgkin’s lymphoma present?

A

Peaks in young adults and elderly
Enlarged, non-tender rubbery superficial lymph nodes
25% have fever, weight loss, night sweats, lethargy

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4
Q

How does non-Hodgkin’s lymphoma present?

A

Superficial lymphadenopathy

Extranodal disease depending on type (gut, oropharynx)

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5
Q

Translocation occurs between which two chromosomes in follicular lymphoma?

A

14 and 18

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CCs - Haematological (3 decks)

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