Catabolism Flashcards

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1
Q

phosphofructokinase

A

Phosphorylates Fructose-6-phosphate. Important regulatory step. Non reversible. Allosteric Enzyme

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2
Q

How is glycolysis regulated

A

High concentrations of ADT allosterically bind to phosphofructokinase,allowing the second phosphorylation event to occur.

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3
Q

How does the Entner Duodoroff pathway differ from EMP

A

The first phase of EMP pathway.
Glucose is only activated by 1 phosphorylation reaction.
Produces 6phosphogluconate which is converted to pyruvate and glyceraldehyde, which enters EMP pathway

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4
Q

What does ED pathway produce

A

1 ATP, 2 Pyruvate, and 1 NADH, and 1 NADPH

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5
Q

What is an important intermediate only in ED and PPS

A

6-phosphogluconate

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6
Q

Do Duodoroff pathway and PPS share an intermediate

A

Yes, 6-phosphogluconate

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7
Q

Enzyme that converts Glucose 6-P to 6-phosphogluconate

A

Glucose-6-phospate-1-dehydrogenase, also produces NADPH

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8
Q

What is unique about PPS and ED somwhat

A

It is an Amphibolic pathway

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9
Q

What is special about NADPH

A

It is used as a source of electrons in biosynthesis reactions

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10
Q

PPS imporatant intermediate

A

Ribulose-5-phophaste, It can be isomerized by various enzylmes. These isomers can made

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11
Q

Eryhtrose-4-phosphate importance

A

Used for aromatic amino acid biosynthesis

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12
Q

of carbons transferred in Transaldolase and transketolase

A

Transketolase transfers 2 carbons and transketolase transfers 3 carbons

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13
Q

TWO enzymes critical for interconversions of sugars

A

Transketolase and Transaldolase

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14
Q

Fermentation

A

catabolism without electron transport system and a terminal electron acceptor

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15
Q

Where does ATP synthesis take place in fermentaiton

A

The conversion of Glyceraldehye-3-phosphate to Pyruvate

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16
Q

Two key intermeediates for most fermentations

A

Pyruvate, and acetyy-CoA

17
Q

Key difference between fermentatation and nonfermentative growth

A

Electron in NADH donates its electrons to ETC in nonfermentative but it is donated back to an organic molecule to regenrate NAD+

18
Q

Other names for TCA cycle

A

Krebs cycle and citric acid cycle

19
Q

Two major roles of TCA cycle

A

Oxidation of pyruvate to CO2 with production of high energy P compounds and reducing equivalents,
Important source of Carbon skeleton during biosyntheis

20
Q

Describe fermentation and respiration

A

Fermentation is the partial breakdown of organic material without net electron transport to a final inorganic electron acceptor.
Respiration is the complete breakdown of organic material with electron transfer to a terminal electron acceptor.

21
Q

Photoheterotrophy

A

find out what this means

22
Q

Important intermediates in sugar, lipid, and amino acid catabolism/

A

In sugar metabolism, its pyruvate.

In lipid meatbolism, its glycerol, and acetate

23
Q

Name the three pathways of catabolism

A

Embden-meyerhoff parnas pathway
Entner-duodoroff pathway
Pentose Phosphate Shunt

24
Q

Important components of Pyruvate dehydrogenase complex

A

NAD->NADH, Pyruvate loses a carbon

25
Q

First step in TCA cycle

A

AcetylCoA donate acetyl group to oxaloacetate

26
Q

How many ATP can FADH2 and NADH make?

A

3 for NADH, 2 for Fadh2

27
Q

How many ATP are made by ETC

A

000000000000000000

28
Q

describe the glyoxylate pathway

A

isocitrate is broken down in glyoxylate and succinate via lyase and then glyoxylate takes an acetyl group from acetylcoa to form malate. no co2 is lost