Catabolism Flashcards
phosphofructokinase
Phosphorylates Fructose-6-phosphate. Important regulatory step. Non reversible. Allosteric Enzyme
How is glycolysis regulated
High concentrations of ADT allosterically bind to phosphofructokinase,allowing the second phosphorylation event to occur.
How does the Entner Duodoroff pathway differ from EMP
The first phase of EMP pathway.
Glucose is only activated by 1 phosphorylation reaction.
Produces 6phosphogluconate which is converted to pyruvate and glyceraldehyde, which enters EMP pathway
What does ED pathway produce
1 ATP, 2 Pyruvate, and 1 NADH, and 1 NADPH
What is an important intermediate only in ED and PPS
6-phosphogluconate
Do Duodoroff pathway and PPS share an intermediate
Yes, 6-phosphogluconate
Enzyme that converts Glucose 6-P to 6-phosphogluconate
Glucose-6-phospate-1-dehydrogenase, also produces NADPH
What is unique about PPS and ED somwhat
It is an Amphibolic pathway
What is special about NADPH
It is used as a source of electrons in biosynthesis reactions
PPS imporatant intermediate
Ribulose-5-phophaste, It can be isomerized by various enzylmes. These isomers can made
Eryhtrose-4-phosphate importance
Used for aromatic amino acid biosynthesis
of carbons transferred in Transaldolase and transketolase
Transketolase transfers 2 carbons and transketolase transfers 3 carbons
TWO enzymes critical for interconversions of sugars
Transketolase and Transaldolase
Fermentation
catabolism without electron transport system and a terminal electron acceptor
Where does ATP synthesis take place in fermentaiton
The conversion of Glyceraldehye-3-phosphate to Pyruvate