Case 1 definitions Flashcards
Morphine sulfate: brand (starts with A lol) type, polymer
Avinza; spansule; uses methacrylate polymer
Morphine sulfate: brand (starts with K), type, what makes pellets?
Kadian; spansule; EC (ethyl cellulose), PEG (poythylene glycol); methacyrlate
Morphine sulfate: brand (starts with MS), polymer matrix, what type of interactions
MS Contin; hydrophilic polymer (HPMC), hydrophoblic polymer (HEC); diffusion of drug into aqueous phase, constant and predictable relationships
Oxycodone HCl: brand, type, what makes up matrix
Oxycodone HCl; dual controlled matrix of hydrophobic polymers; GI fluid enters tablet matrix and dissolves entrapped drug
Hydrocodone bitartrate: band, pellet types; why we need it
ZohydroER; coated carrier beads in hard gelatin capsules, hydrocodone bitartrate, rate controlling polymers, drug is released by diffusion out of the polymers; opioids maintain pivotal role in managing chronic pain
NSAIDS; brand, what it treats
Vimovo, treats osteoarthritis & RA; decreased risk of developing NSAID associated gastric ulcers
what covers the sugar of spansules
microcrystalline cellulose
methylphenidate HCl
Ritalin LA / spansules
amphentamine salt
Adderall XR / spansule
what is the coating in delayed release
waxes and cellulose acetate phthalate (CAP)
aspirin prilosec
delayed release
ambien CR
Zolpidem ER / repeat action tablets
two tpes of microencapsulation
coacervation / spray drying
micro-K enencaps
potassium chloride
what is used in slowly eroding matrix tablets
hydrophillic cellulose polymer
Vermapril HCl
Calan? / slowly eroding matrix tablets
osmotic agents
NaCl or mannitol
example of osmotic pumps
Methylphenidate HCl (Concerta)
Tussinex
hydroodone chloripheniamine / ion exchange resins
mechs of oral MRDF (3 ways)
modify drug dissolution by controlling access of biologic fluids using barrier coatings; control diffusion rate from dosage forms; release after interaction between drug substance or excipient barrier and site specific biologic fluids
modify drug dissolution by controlling access of biologic fluids using barrier coatings (4)
spansules; DR; RA; microencapsulation
control diffusion rate form dosage forms (2)
slowly eroding matrix tablets; inert plastic matrix tablets
release after interaction between drug substance or excipient barrier and site specific biologic fluids (3)
osmotically controlled systems; osmotic pumps; ion exchanges resins
Nitroglycerin Sublingual
Nitrostat, NitroQuck / antianginal, antihypertensive, vasodilator / molded tablet /
