Cardiovascular Flashcards
cardiovascular system function
rapid transportation over long distances:
- nutrients
- fuel
- respiratory gases
- remove waste
- circulate hormones
- circulate immune cells and antibodies
- regulate pH
- regulate water balance
- thermoregulation
heart
- “pump”
- right ventricle: blood into lungs
- left ventricle: blood to body
vascualture
- carry the blood
- arteries: away from heart
- veins: to the heart
blood
- carries nutrients, respiratory gases, and metabolic wastes
- erythrocytes
- leukocytes
- platelets
diffusion
- movement of molecules from higher concentration/pressure to lower concentration/pressure
diffusion regulation
- distance: inverse relationship
- temperature: direct relationship
- density: inverse relationship
- mass/size: inverse relationship
- surface area: direct relationship
- thickness: inverse relationship
- permeability: direct relationship
- gradient: direct relationship
insects
- open circulation
- hemolymph: circulatory fluid
- absent of hemoglobin
- “heart”: chambers ending in ostioles (valve) that pumps hemolymph
fish
- single-loop
- single heart: no left/right ventricle/atrium or venous/arterial
- 2 chambers: ventricle and atrium
- oxygenation at Gill capillaries
amphibians and reptilians
- double-loop
- 3 chambers: 2 atria and 1 ventricle (no/little O2 rich and O2 depleted blood mixing due to close proximity of the aorta and the ventricle)
- left atrium –> ventricle –> systemic capillaries –> right atrium –> ventricle –> pulmoncutaneous circuit –> left atrium
crocodile/alligator
- 4 chambers: left and right atrium, left and right ventricle
- valve between right ventricle and pulmonary circulation closes to allow “breathing” underwater
avian and mammalian
- right heart: pulmonary circulation
- left heart: systemic circulation
- double-loop
- 4 chambers: left and right atrium, left and right ventricle
hemodynamics
- volume
- flow
- pressure
- resistance
- compliance
stroke volume (SV)
- volume of blood pumped out of the heart per contraction (~70 mL)
- SV=end-diastolic volume (EDV)-end-systolic volume (ESV)
venous return
blood flow from periphery back to the atrium
cardiac output (CO)
- amount of blood the heart pumps per minute
- CO=SV*HR
flow
- peripheral organs are arranged in parallel to each other
- heart, lungs, and the peripheral organs are arranged in series to each other
- flow=area*mean velocity
- proportional to perfusion pressure
- greater flow in the middle of the vessel
blood vessel comparison
- number: aorta < vena cava < artery < veins < arterioles < venules < capillaries
- diameter: aorta > vena cava > artery > veins > arterioles > venules > capillaries
- length: aorta > vena cava > artery > veins > arterioles venules > capillaries
- thickness: aorta > vena cava > artery > veins > arterioles venules > capillaries
- surface area: aorta < vena cava < artery < veins < arterioles < venules < capillaries
- flow: aorta > artery = vena cava > arteriole = venules > capillaries
arteriole
- more muscular
- more elastic
- no valve
vanule
- les muscular
- contains a valve
blood pressure
- force exerted by blood on the wall of the blood vessels
- pressure=perfusion pressure/resistance
- higher in systemic circulation than pulmonary circulation due to lower compliance and higher resistant (due to the more muscular characteristic)
resistance
- cause by friction between the vessel wall and the blood
- increased length –> increased friction –> increased resistance
- R=(8viscositylength)/(pi*radius^4) –> R is proportional to 1/r^4: only valid for laminar flow
- series: R=R1+R2, R>R1 or R2
- parallel: 1/R=(1/R1)+(1/R2), R<R1 or R2
laminar flow
flow all in the same direction
turbulent flow
flow not all in the same direction
compliance
- ability of the blood vessel to stretch
- compliance=change in volume/change in transmural pressure –> transmural pressure=pressure inside-pressure outside
four chambers of the heart
- right atrium
- right ventricle
- left ventricle
- left atrium
great vessels of the heart
- superior vena cava
- inferior vena cava
- right pulmonary artery
- right pulmonary veins
- aorta
- left pulmonary artery
- left pulmonary veins
- pulmonary trunk
separations in the heart
- inter-atrial septum: divides the left and right atrium
- inter-ventricular septum: divides the left and right ventricle