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TT DD ex 3 and BL ex 2 > Bugs and drugs > Flashcards

Bugs and drugs Flashcards

1
Q

Gram + cocci

A

Staphylococcus
Streptococcus
Enterococcus

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2
Q

Gram - cocci

A

Neisseria gonorrhea

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3
Q

Gram - bacilli

A

E. coli

Pseudomonas

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4
Q

Gram + anaerobic bacilli

A

Clostridia

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5
Q

Gram - anaerobic bacilli

A

Bacteroides

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6
Q

Atypical

A

Chlamydia

Mycoplasma

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7
Q

Which cell wall synthesis inhibitors are absorbed PO?

A 
PCN -V
Oxacillin
Dicloxacillin
Amoxicillin
Ampicillin
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
All cephalosporins except
- Cefazolin (1st)
- Cefoxitin (2nd)
- Ceftriaxone (3rd)
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Vanc when treating C.Diff
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8
Q

Which cell wall synthesis inhibitors are administered IV?

A 
PCN-G
Methicillin
Ticarcillin
Piperacillin (PIP-TAZO)
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
3 of the Cephalosporins:
- Cefazolin (1st)
- Cefoxitin (2nd)
- Ceftriaxone (3rd)
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Carbapenems
\_\_\_\_\_\_\_\_\_\_\_\_\_
Vanc except for C. Diff

Pa-pa-sa-sa-va!

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9
Q

Which protein synthesis inhibitors are absorbed PO?

A

All the protein synthesis inhibitors except:
Streptogamins
AGs

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10
Q

Which protein synthesis inhibitors are administered IV?

A

Streptogamins

AGs

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11
Q

Which inhibitor of DNA fxn are absorbed PO?

A

FQ
- Cip, Levo, Mox

Nitrofurantoin
Metronidazole

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12
Q

Sulfonamides are absorbed PO or administered IV?

A

PO

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13
Q

Drugs that distribute to CSF

A 
PCN (if tissue is inflammed)
Ceftriaxone (3rd gen ceph)
Carbapenams
\_\_\_\_\_\_\_\_\_\_\_
Chloramphenicol
Metronidazole
Sulfonamides
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14
Q

Drugs that distribute to urine

A

AG
FQ
- (Cip, Levo)
NF

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15
Q

Drugs that distribute to bone

A

Clindamycin

Metrinidazole

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16
Q

Drugs that distribute to lungs

A

Macrolides (ACE)
FQ
- Levo, Mox

17
Q

Drugs that distribute to bone (Bad)

A

TCN

18
Q

Drugs that distribute to teeth (Bad)

A

TCN

19
Q

Drugs that distribute to kidney (Bad)

A

AGs

20
Q

Drugs that contribute to 8th nerve damage (Bad)

A

AGs

21
Q

Drugs that distribute to fetus (Bad)

A 
Cephalosporins
Macrolides (ACE)
TCN
\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Sulfonamides
22
Q

Drugs that are eliminated Non-renally can cause what 3 negative side effects?

A
  1. drug-drug interactions,
  2. genetic polymorphisms in metabolizing enzymes, ]
  3. potential for hepatotoxicity:
23
Q

List Drugs that are eliminated Non-renally

A 
D - oxycyclin
Q - uinolones (mox)
C - lindamycin
R - rifampin
I - soniazid
M - etronidazole
E - rythromycin like drugs (ery and Azi are biliary excretion)
S - ulfonamides
24
Q

Which DQCRIME drugs are inhibitors of P450?

A

Quinolones

Erythromycin

25
Q

Which DQCRIME drugs are inducers of P450?

A

Rifampin

26
Q

Metronidazole and Erythromycin like drugs are at risk for DDI, but via different mechanisms. Explain

A

Metronidazole: drug-drug interaction with alcohol due to inhibition of aldehyde metabolism (Antabuse reaction)

Erythromycin-like:  drug-drug interactions due to inhibition of P450 (Clar-Ery not Azi)
27
Q

Renally excreted drugs

A 
PCN
Cephalosporins
Carbapenams
Vanc
\_\_\_\_\_\_\_\_\_
AGs
FQ (Cip, levo)
28
Q

-Cidal drugs

A 
All the CW synth inhibitors
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Oxazolidinones for strep
Streptogamin (whn used synergistically w/ quinupristen)
AGs
\_\_\_\_\_\_\_\_\_\_\_\_
All inhibitors of DNA fxn
29
Q
  • Static drugs
A 
Macrolides (ACE)
Clindamycin
Chloremphenicol
Oxazolidinones
TCN
  • Basically All protein synthesis inhibitors except:
    Oxazolidinones for strep
    Streptogamin (whn used synergistically w/ quinupristen)
    AGs
30
Q

Which Protein synthesis inhibitors inhibit the 30s subunit?

A

TCN

AGs

31
Q

Narrow spectrum drugs list

A

PCN
VANC
AGs

32
Q

Extended spectrum drug list

A 
Extended spectrum PCN
Anti-pseudomonal (PIP/Tazo)
Cephalosporin
Carbapenam (wide spectrum)
\_\_\_\_\_\_\_\_\_\_\_\_\_
Macrolides
FQ
33
Q

Broad spectrum drug list

A

Chloramphenicol
TCN
Sulfonamides

TT DD ex 3 and BL ex 2 (21 decks)

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