Breast Basics and Inflammation

Question 1

2 Layers of Epithelium in Lobules/Ducts

Answer 1

Luminal cell layer - inner, responsible for milk production (in lobules)
Myoepithelial cell layer - outer, contractile cells

Question 2

Highest Density of Ducts/Lobules

Answer 2

Upper outer quadrant

Question 3

Gactorrhea and Breast Cancer

Answer 3

Not a symptom

Question 4

Acute Mastitis (causative agent, 2 tx)

Answer 4

S. aureus in breast feeding
Keep feeding (drainage) and dicloxacillin

Question 5

Periductal Mastitis (what it is, demographic/pathophys, presentation)

Answer 5

Inflammation of subareolar ducts
In smokers, because smoking causes relative Vit A deficiency which is required to maintain specialized epithelium, so you get squamos metaplasia in ducts causing blockage/inflammation
Presents as subareolar mass with nipple retraction (from fibrosis)

Question 6

Periductal Mastitis (what it is, demographic/pathophys, presentation)

Answer 6

Inflammation of subareolar ducts
In smokers, because smoking causes relative Vit A deficiency which is required to maintain specialized epithelium, so you get squamos metaplasia in ducts causing blockage/inflammation
Presents as subareolar mass with nipple retraction (from fibrosis)

Question 7

Mammary Duct Ectasia (what it is, demographic, presentation)

Answer 7

Inflammation with dilation (ectasia) of subareolar ducts

As mass in multiparous postmenopausal women - so worried about cancer. But GREENISH BROWN DISCHARGE

Question 8

Fat Necrosis

Answer 8

Usually after trauma, can show calcification on mammogram confounding shit