Brain & Cranial Nerves Flashcards
Which 2 lobes are proportionally bigger for humans compared to other apes?
Frontal and Parietal
Developmental precursor to skin & CNS?
Ectoderm
Neurulation
- Gene signalling from notochord causes rapid growth of nearby ectoderm
- Thickening neural crest folds to form neural tube
- Brain forms from cranial end of neural tube
Brain differentiation? (3 main developmental structures -> corresponding adult structures?)
What age does neural connectivity peak?
2 years old (via rapid dendrite growth)
Synaptic pruning
Unused connections (dendrites) are pruned in adolescence
Continues (more slowly) in adulthood
Excessive pruning may cause schizophrenia
Which 2 arteries supply the brain?
Carotid and vertebral
Vertebral arteries
What do external and internal carotid arteries each supply?
External: face and scalp
Internal: brain
Internal carotid
Circle of Willis
Circular arterial connection at the base of the skull; creates an anastomosis
Anastomosis
Series of connections between blood vessels; provides redundant blood flow in case of blockage
Brain aneurysm
Hemorrhagic stroke
Blood-brain barrier
Unlike most capillaries, brain vessels have tight junctions (no pores), limiting the passage of most substances to the brain.
Bacteria and fats can’t make it through to the brain
What is the brain suspended in?
Cerebrospinous fluid
Fills the subarachnoid space; provides buoyancy and cushioning
Where is CSF produced and stored?
Ventricles
A series of connected spaces/canals in the center of the brain
arachnoid granulations