boards 9 Flashcards
what things does activated charcoal not work for
lithium, iron, cyanide, hydrocarbons, alchol, alkali, acid
what to use whole bowel irrigation for
sustained release drugs, iron, lithoium, drug packers, lead - CI with ileus obstruction
what drugs eliminated with urine alkalizationa
salicylates, phenobarb, INH - goal ph 7-8, replace K+
what drugs do you need to use HD for
salicylates, lithium, methanol, isopropanolol, ehtylene glycol, phenobarb, theophylline
what characteristics of drugs do you use HD on
low protein binding, low MW, small volume of distrib, water soluble
antidote for acetaminophen/ arsenic/ aspirin
NAC, BAL DMS, alkaline diuresis HD
antidote for B blocker, barb
Glucagon, intralipids, Alkaline diruesis and HD
antidoite for CA channel blocker, carbamate, CO
calcium, glucagon gluc/ins, intralipids ATROPINE, 100% o2
antidote for Warfarin, cyanide, digitalis
FFP vit k PPCC, hydroxycobalamin, na nitritem na thosulfate, DIGIBIND fab ab
what cause sincreased anion gap
MUDPILES- methanol/metformin, uremia, DKA, paraldehyde, IronINH, Lactic acidosis, ethylene glycol salicylates
increased osmolar gap
acteone, isopropanol, methanol, ethylene glycol, mannitol, ketoacidosis, ethanol
anticholinergic tox are eyes dilated or constricted
DILATED
causes of antich toxidrome
antihistamines, atropine, TCA, antiparkinsons, jimsonweed
treatent of cardiac complications of anticholinergic
lido or amio for ventricular dysrhthhma, na bicarb for Wide complex tachy, physostigmine
sympathomemtic toxidrome sxs- and hows it differ from antich
aigtated, sz, htn, tachy, sweating, dilated pupils - different because antich IS DRY NOT WET
cholinergic toxidrome treatment
atropine tirate to killer B - bradycardia, bhornchorhea, bronchospasm , 2-pam pralidoxome
what are the nicotiic effects of the cholinergic toxidrome
muscular weakness fasciculations and resp failure
mechanism of cholinergic toxidrome
inhibit cholinesterase- increased ACH
tylnoel nomogram keys
level greater than 140 at 4- they GET 140 mg/kg NAC- prevents toxic hepatic metaboolites from forming by using a cofactor
cn IV palsy, nystagmus, ataxia, global confusion
Wenickes encephalopathy - thamine b1
confabulation and retrograde amnesia
korsakoffs
anion gap acidosis, inc osmolar gap, visual symptoms, hx pain thinner, wood alcohol
methanol- nontoxic but metabolized to formic acid- sxs delayed 12-18 hrs - seziures, visual changes
treatment of ethanol
4pm- fomepizole, dilayiss
antifreeze, pain, solvents, anion gap acidosis, inc osmola gap - oxalic acids precipiatet in urine to form oxalata crysteal
ethylene glycol- renal failure, hematuria, hyopocalcemia, treatment fomepizole - inhibits alcohol dehydregenase - excretes EtG from urine
rubbing alcohol, CNS depression, ketosis but NO ACIDOSIS- normal anion gap, inc osmolar gap
isopropyl etoh, - pulm edema, hypotension, HD
young woan saw gyn recently started on medication now with flushing, diaphoresis, nv headache hypotension seizures dhysrhythmias
antabuse disulfiram rxn - Etoh + flagyl
overdose that causes cutaneous bullae
bartibutrates, tx charcoal, alkalinzation
how does CO affect oxy hb curve
shifts to LEFT, inhbits the release of oxygen from hemoglobin
descent injuries in scuba
squeeze syndroes- barotitis media - TM rupture, blocked eustacean tube , vertigo
pulmonary barotrauma- uncontrolled ascent problems
burst lung- ptx, pneummediastinum, hemothoaix or AIR GAS EMBOLISM- sudden - LOC and seizures - air emboli- has to go into DIVE CHAMBER