boards 3 Flashcards
casues of glomerulonephritis
IC/abx in glomeruli- dont make pee, retain fluid, hypertesntisve - post strep GN, wegeners, goodpasteurs, lupus, HUS TTP IGA nephropathy
oliguria, edema, pyuria, RBC casts, hypertension
acute nephritic syndrom e, t steroids
acute interstitia nephritis
allergic reaction, immune mediated- from pcn, sulpha, diuretics, infxn - EOSINOPHILS, rash
leading cause of renal failure
ATN - ischemic- olugirua, from trauma/sepsis- toxic- from constast media, myoglobin, hemolysis, MM, aminoglycosides, ethylene glycol
how does rhabdo cause ATN
myoglobin clogs tubules, positive urine HEME but no RBC on micro, very high elevation of creatinine quicly , CK > 5x elevated
prerenal vs renal failure
renal failure has FENA >1% and high urina sodium, no BUN/cr
RBC casts in urine
glomerular disease, nephritic syndrome
WBC casts
interstitium, pyelo AIN
eosinophils-
AIN
granular casts (Cell debris)
tubule, ATN
hyaline casts ( acellular)
post or pre renal
pink urine work up
rbcs- hematuria - nephritic syndrom eor stone , if NO RBCS then myoglobinuria or hemoglobinuria - intravascular hemolysis, DIC TTP HUS
nephritic vs nephrotic
nephritic is acute, oliguria, htn, casts in Ua, nephrotic is chronic, massive protein, edema, HLD, hypo alb, thrommbic diathesis, UA with no cells
caus sof nephrotic syndrome
DM SLE HIV MM
autosomal dominant, flank pain and hematuria, progressive renal failure, what is the associated complication
PCKD - cerebral aneurysm, SAH - can also have cysts in liver and spleen
indiation for dialysis in uremia
has ompliaitons such as encephalitis, pericardits, bleeding, BUN >100-150, toxins
ESRD complications
CAD, refractory htn, tamponade, uremic pericarditis, pulm edema, have all cell linesaffected- anemia, infxn bleeding, cocner for risk of SDH
ESRD with hyper K
bradyasystolic arrest, Ca gluconate, shift with bicarb, insulin d5- albuterol, elimiate with polystyrene
hypo K after dialysis
V fib, PVCs
most common complication ESRD
hypotension, second is bleeding
bleeding in ESRD causes
bleeding, give DDAVP, cloting - thrill is gone- inject thromblytic, surgical removal, infection- staph gram negatives, highoutput failure
AMS casues in ESRD
hypotension, hypogly, hyperca, sdh
peritoneal fluid in peritoneal diaslysis patient and bugs
100 WBC in anylysis, 50% pmn, staph epidermidits and s aureus
criteria for UTI
sxs plus 100 CFU
complicated UTI bugs
klebsiela, preotus, pseudomonsas, enterobacter, staph, grp d strep
do you treat asxs bacteriuria
only in pregnancy to prevent pyelo