Blueprints 1, 3, 12, 22, 28 Flashcards
when will a urine preg test be positive
at the time of a missed period
from what organ do they hormones of pregnancy that affect every organ come from
the placenta
what CV changes occur in pregnancy?
increase CO, decrease SVR (progesterone-> SM relaxation), decrease BP ( but return to normal by 24 weeks)
3 common screening tests for fetal abnormalities
MS-AFP (maternal serum AFP) : 15-18 weeks
and triple screen( AFP, hCG, and estriol)
quad: add on inhibin
3 diagnostic tests for screening abnormalities
amniocentesis, CVS, ultrasound
tests for fetal status antepartum
BPP= U/S and NST (fetal nonstress test- activity over 30 minutes- good if 2 accelerations 15 beats above for 15 sec). BPP>10 is reassuring.
OCT (oxytocin challenge test- goal is 3 contractions every 10 minutes)
how early can you see gestational sac on transvag US
5 weeks, fetal heart at 6 weeks
chadwick sign
blueish color or vagina and cervix during prgenancy
NAAGELS rule for EDD. US estimation?
subtract 3 months from LMP and add 7 days. U/S should be within 1 weeks first TM, 2 weeks second TM, 3 weeks third trimester
lung changes in pregnancy
TLC decreased 5% but tidal volume increases 30-40% which causes decrease in expiratory respiratory reserve 20%
paco2 in pregnancy
decreases to 30 mmHg from 40 mmHg likely caused by progesterone. gradient increases oxygen delivery and CO2 removal from fetus
kidney in pregnancy
GFR increases 50%, BUN and creatinine decrease by 25%. even though increased aldo and increased NA reabsorption, plasma levels of sodium stay the same
heme in preg
dilutional anemia, incresed WBC, hypercoagulable
hPL
produced in placenta for ensuring constant nutrient supply to fetus-> lipolysis with increase in circulating FA. HPL is insulin antagonist=diabetogenic.
preg and thyroid
increased TBG so slight increase in total T3 and T4 but same level of free T3/4 and stimulates TSH a little. overall euthyroid.
third trimester screening tests
hematocrit (iron supplement), RPR/VDRL, glucose loading test
when do most fetal congenital abnormalities occur
embryogenesis