Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Review For Board Exam > Blood Banking Pre-Test > Flashcards

Blood Banking Pre-Test Flashcards

1
Q

Recipient of first blood transfusion in history

a. Pope Innocent VI
b. Pope Benedict IV
c. Pope Innocent VII
d. Pope Benedict VI

A

Pope Innocent VII

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Which blood group is associated with severe hemolytic transfusion reaction (HTR)?

a. Kidd
b. ABO
c. Rh
d. A and B

A

ABO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which blood group is associated with severe hemolytic disease of the newborn (HDN)?

a. MNS
b. Duffy
c. Rh
d. ABO

A

Rh

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

A blood donor has the genotype: hh, AB. What is his red blood cell phenotype?

a. “A” and “B”
b. “B”
c. “O”
d. “AB”

A

“O”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Nature of ABO antibodies

a. IgG
b. IgA
c. IgM
d. AOTA

A

AOTA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The antibody in the Lutheran system that is best detected at lower temperatures is:

a. anti-Lua
b. anti-Lub
c. anti-Lu3
d. anti-Lu ab

A

anti-Lua

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

A cell that is not actively dividing is said to be in:

a. Interphase
b. Prophase
c. Anaphase
d. Telophase

A

Interphase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What blood type is not possible for an offspring of an AO and BO mating?

a. AB
b. A or B
c. O
d. All are possible

A

All are possible

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Acquired B antigens have been found in:

a. Bombay individuals
b. Group O persons
c. All blood groups
d. Group A persons

A

Group A persons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which typing results are most likely to occur when a patient has an acquired B antigen?

a. Anti-A 4+, anti-B-3+, A1 cells neg, B cells neg

b. Anti-A 3+, anti-B neg, A1 cells neg, B cells neg

c. Anti-A 4+, anti-B 1+, A1 cells neg, B cells 4+

d. Anti-A 4+, anti-B 4+, A1 cells 2+, B cells neg

A

Anti-A 4+, anti-B 1+, A1 cells neg, B cells 4+

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What may be done to RBCs before
transfusion to a patient with cold
agglutinin disease in order to reduce the possibility of a transfusion reaction?

a. Irradiate to prevent graft-versus-host-disease (GVHD)

b. Wash with 0.9% percent saline

c. Warm to 37°C with a blood warmer

d. Transport so that temperature is maintained at 20°C–24°C

A

Warm to 37°C with a blood warmer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Most common transfusion
transmitted infection

a. HIV
b. Viral hepatitis
c. Syphilis
d. Both A and C

A

Viral hepatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which physical examination result is cause for rejecting a whole-blood donor?

a. Weight of 105 lb
b. Pulse of 75
c. Temperature of 99.3°F
d. Diastolic pressure of 110 mm Hg

A

Diastolic pressure of 110 mm Hg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

A woman begins to breathe rapidly
while donating blood. Choose the correct course of action.

a. Continue the donation; rapid breathing is not a reason to discontinue a donation

b. Withdraw the needle, raise her feet, and administer ammonia

c. Discontinue the donation and provide a paper bag

d. Tell her to sit upright and apply a cold compress to her forehead

A

Discontinue the donation and provide a paper bag

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

The optimum storage temperature for RBCs, Frozen is:

a. -80°C
b. -20°C
c. -12°C
d. 4°C

A

-80°C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Shelf-life of FFP (-65°C)

a. 4 years
b. 5 years
c. 6 years
d. 7 years

A

7 years

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Shelf-life of granulocyte concentrate

a. 24 hours
b. 24 days
c. 12 hours
d. 12 days

A

24 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Process of removing antibody in
the serum?

a. Absorption
b. Elution
c. Adsorption
d. Dilution

A

Adsorption

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Process of removing antibody from
RBC membrane?

a. Absorption
b. Elution
c. Adsorption
d. Dilution

A

Elution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

To remove Wharton’s jelly, cord cells should be washed?

a. 10x
b. 2x
c. 3-6x
d. 6-8x

A

6-8x

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Who discovered ABO Blood
Group?

a. Karl Landsteiner
b. Joseph Murray
c. Edward Jenner
d. Rosalin Yallow

A

Karl Landsteiner

22
Q

What immunodominant sugar
confers B blood group
specificity?

a. D-galactose
b. L-fucose
c. N-acetylgalactosamine
d. L-glucose

A

D-galactose

23
Q

Select the ABO phenotypes, in
order from most frequent to
least frequent, that occur in
whites:

a. A, B, O, AB
b. O, A, B, AB
c. B, A, AB, O
d. AB, O, B, A

A

O, A, B, AB

24
Q

Criteria for Rhogam candidacy:

a. Mother must be Rh negative
b. The mother should have anti-D
c. Both
d. NOTA

A

Mother must be Rh negative

Note:

RhoGAM is a medicine that stops your blood from making antibodies that attack Rh-positive blood cells.

25
Q

What antibody in MNS blood group is enhanced by acidic pH?

a. anti-M
b. anti-N
c. anti-S
d. anti-s

A

anti-M

26
Q

First law of Mendel’s law – every
individual contains 2 alleles for each trait and these alleles segregate

a. Law of Independent Assortment
b. Law of Segregation
c. Law of Dominance
d. Law of Recessiveness

A

Law of Segregation

27
Q

It refers to genes usually come in
pairs

a. phenotype
b. genotype
c. homozygous
d. heterozygous

A

genotype

Notes:
-Phenotype- An individual’s observable traits, such as height, eye color and blood type.

-Homozygous- Having inherited the same versions (alleles) of a genomic marker from each biological parent. E.g. BB or bb

-Heterozygous- Having two different alleles of a particular gene or genes. E.g. Bb

28
Q

A patient had a transfusion reaction to packed red blood cells. The medical laboratory scientist began the laboratory investigation of the transfusion reaction by assembling pre-and post-transfusion specimens and all paperwork and computer printouts.

What should he do next?

a. Perform a DAT on the post-transfusion sample

b. Check for a clerical error(s)

c. Repeat ABO and Rh typing of patient and donor unit

d. Perform an antibody screen on the posttransfusion sample

A

Check for a clerical error(s)

29
Q

Why do Rh-negative women tend to
have a positive antibody screen
compared to Rh-positive women of
childbearing age?

a. They have formed active anti-D

b. They have received RhIg

c. They have formed anti-K

d. They have a higher rate of transfusion

A

They have received RhIg

30
Q

Who developed the gel test?

a. Dr. Yves Lapierre
b. Dr. John Michaelis
c. Dr. Ethan Lapierre
d. Dr. Anton van Leeuwenhoek

A

Dr. Yves Lapierre

31
Q

hat are perfluorocarbons?

a. They are used as substitute for the known A and B cells

b. Replacement of serum sample

c. They are used as disinfectants

d. Blood substitute

A

Blood substitute

32
Q

Length of centrifugation with LISS
is:

a. 10-30 seconds
b. 5-8 mins
c. 10-20 seconds
d. 10-15 mins

A

10-15 mins

33
Q

Platelet concentrate is prepared
through:

a. 8 hard spins
b. hard spins
c. Pulse of 75
d. Light spin then hard spin

A

Light spin then hard spin

34
Q

The following results were obtained
on a 51-year-old male with hepatitis C:

Anti-A = 4+
Anti-B = 4+
Anti-D = 3+
A1 cells = 0
B cells = 0

What should be done next?

a. Retype the patient’s sample to confirm group AB positive

b. Repeat the Rh typing

c. Run a saline control in forward grouping

d. Report the patient as group AB, Rh positive

A

Run a saline control in forward grouping

Note:

In the case of an AB-positive person,
a saline control must be run in forward grouping to obtain a negative reaction; this will ensure agglutination is specific in the other reactions.

35
Q

Treatment for patients who have
TACO:

a. Iron-chelating agents

b. Use thiol

c. IV diuretics, therapeutic phlebotomy

d. AOTA

A

IV diuretics, therapeutic phlebotomy

Note:

Transfusion-associated circulatory overload (TACO) is a common transfusion reaction where pulmonary edema due to excess volume or circulatory overload results in the patient experiencing acute respiratory distress.

36
Q

Why is testing a pregnant woman for weak D not required?

a. An Rh-negative fetus may yield false positive results in a fetal maternal bleed

b. An Rh-positive fetus may yield false positive results in a fetal maternal bleed

c. D antigen strength decreases during pregnancy

d. D antigen strength increases during pregnancy

A

An Rh-positive fetus may yield false positive results in a fetal maternal bleed

37
Q

What does the genotype —/— represent in the Rh system?

a. Rh negative
b. D mosaic
c. Rhnull
d. Total Rh

A

Rhnull

38
Q

What type of blood should be given to an individual who has an anti-Leb that reacts 1+ at the IAT phase?

a. Blood that is negative for the Leb antigen

b. Blood that is negative for both the Lea and Leb antigens

c. Blood that is positive for the Leb antigen

d. Lewis antibodies are not clinically significant, so any type of blood may be given

A

Blood that is negative for the Leb antigen

39
Q

What does the 3+3 rule ascertain?

a. An antibody is ruled in

b. An antibody is ruled out

c. 95% confidence that the correct antibody has been identified

d. 95% confidence that the correct antibody has not been identified

A

95% confidence that the correct antibody has been identified

40
Q

How would autoantibodies affect compatibility testing?

a. No effect

b. The DAT would be positive

c. ABO, Rh, antibody screen, and crossmatch may show abnormal results

d. Results would depend on the specificity of autoantibody

A

ABO, Rh, antibody screen, and crossmatch may show abnormal results

41
Q

What does a minor crossmatch consist of?

a. Recipient plasma and recipient red cells

b. Recipient plasma and donor red cells

c. Recipient red cells and donor plasma

d. Donor plasma and donor red cells

A

Recipient red cells and donor plasma

Note:
Major crossmatching is a mandatory test that checks to see if the blood recipient has any antibodies that might resist the donor’s blood cells. To do this test, blood cells from the donor are combined with blood serum from the recipient. So opposite for minor crossmatching.

42
Q

A technologist removed 4 units of blood from the blood bank refrigerator and placed them on the
counter. A clerk was waiting to take the units for transfusion. As she checked the paperwork, she
noticed that one of the units was leaking onto the counter. What should she do?

a. Issue the unit if the red cells appear normal

b. Reseal the unit

c. Discard the unit

d. Call the medical director and ask for an opinion

A

Discard the unit

43
Q

What laboratory component in automation is essential to flag discrepancies with previous results?

a. Staff automation training
b. Preventive maintenance program
c. Vendor relationship
d. LIS

A

LIS

44
Q

Given the following data:

DAT (Anti-IgG) = 2+mf
Antibody screen AHG phase
SC I = 2+
SC II = 0
Auto = 0

Predict the condition consistent with the laboratory
results.

a. TRALI

b. Delayed hemolytic transfusion reaction (DHTR)

c. Warm autoimmune hemolytic anemia (WAIHA)

d. TACO

A

Delayed hemolytic transfusion reaction (DHTR)

45
Q

What transfusion reaction has many clinical signs that
mimic an acute hemolytic transfusion reaction?

a. Transfusion-related acute lung injury (TRALI)

b. Bacterial contamination

c. TACO

d. Allergic

A

Bacterial contamination

46
Q

What is the name of the test that predicts the severity of Hemolytic disease of the fetus and newborn (HDFN) based on amniotic fluid?

a. Liley
b. Rosette
c. Kleihauer-Betke
d. Blood smear

A

Liley

47
Q

What is the name of the procedure that aspirates a fetal blood sample for testing?

a. Cordocentesis
b. Intrauterine transfusion
c. Amniocentesis
d. None of the above

A

Cordocentesis

48
Q

When can a person donate blood after a plateletpheresis collection?

a. 8 weeks
b. 56 days
c. 2 days
d. 4 weeks

A

2 days

49
Q

Which type of review does not require direct discussion between the ordering clinician and transfusion service personnel?

a. Discontinuous prospective
b. Targeted prospective
c. Concurrent
d. Retrospective
e. Prospective

A

Retrospective

50
Q

The majority of HLA antibodies belong to what immunoglobulin class?

a. IgD
b. IgE
c. IgG
d. IgM

A

IgG

Review For Board Exam (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions