Blood Flashcards
Hematocrit (Formed Elements)
45%
RBC
WBC
Liquid Matrix (plasma)
55%
Water-92%
Proteins- 7%
Electrolytes- 1%
Erythrocytes
Most Abundant Cell 99.9% of formed elements Upon maturity they lose organelles Life span of 120 days one cell= 280 million hemoglobin molecules
One drop of blood=
260 million RBCs
Adult Females
4.9 million RBC
Adult Males
5.4 million RBC
Hemoglobin
4 protein chains= carry small amount of CO2
Consists of Iron-O2 binds to
Biliverdin- stabilizes iron
Antigens
molecules that cause immune reactions
exist on cell surfaces
may serve as cell recognition markers
Antibodies
Proteins known as immunoglobulins
Produced by plasma cells
Attach or bind to specific antigens
Eosinophils
secrete antihystamenes
T Cells
attack foreign cells
B cells(when active)
plasma cells= secrete antibodies
Basophils
secrete hystamenes and heparin (prevents blood from clotting)
Monocytes
Macrophages
Platelets
cell fragments that help blood clot
Fibrinogen
blood clotting
Globulin
transport proteins or antibodies
Albumin
influences osmosis (most abundant protein in blood)
Hematocrit (formed elements)
45% of blood
RBC
WBC
Liquid matrix (plasma)
55% of blood
Water- 92%
Proteins- 7%
Electrolytes- 1%
Blood is what type of connective tissue?
fluid connective
Spectrin
keeps red blood cells flexible
Hemoglobin
4 protein chains
Carries small amount of CO2
Heme consists of ..
Iron-O2 binds to
Biliverdin- stabilizes iron
Antigens
molecules that cause immune reactions
exist on cell surfaces
may serve as cell recognition markers
Antibodies
proteins known as immunoglobulins
produced by plasma cells
attach or bind to specific antigens
Type A
Antigen A Anti-B antibodies Receive blood from A and O Donate blood to A and AB Donate plasma to A and O Receive plasma from A and AB
Type B
Antigen B Anti-A antibodies Receive blood from B and O Donate blood to B and AB Donate plasma to B and O Receive plasma from B and AB
Type AB
Antigens A and B Neither antibodies Receive blood from A, B, AB, and O Donate blood to AB Donate plasma to A, B, AB, and O Receive plasma from AB
Type O
Neither antigens Both antibodies Receive blood from- O Donate blood to A, AB, B, and O Donate plasma to O Receive plasma from A, AB, B, and O
Universal plasma donor
AB- no antibodies
Universal blood donor
O- no antigens
Rh positive individuals
carry the antigen
have no Rh antibodies
Rh negative individuals
do not carry the antigen
naturally do not have the antibody
once exposed to Rh antigen, they can develop the antibodies
Rhogam Shots
antibody that covers up Rh antigens
Blood cells come from ..
Mesoderm
Erythroblast
immature red blood cell that contains all organelles
Reticulocyte
RBC that has lost all of its organelles, and its nucleus last
Erythropoeisis
the formation of erythrocytes
Erythropoietin (EPO)
stimulates erythropoiesis
shortens time of maturation
Erythropoeisis is influenced by ..
hypoxia nutrition high altitude damage to lung tissue poor health
Spleen
graveyard of erythrocytes
Pernicious Anemia
deficiency of intrinsic factor
Aplastic Anemia
destruction to myeloid tissue
Polycythemia
elevated formed elements (mainly erythrocytes)
Hemorrhagic Anemia
blood loss
Hemolytic Anemia
destruction of erythrocytes
Transfervin
transports iron in the blood
Agranulocytes
Monocytes
Lymphocytes- t cells, b cells, nk cells
Granulocytes
basophils, neutrophils, eosinophils