Block 4 L4 immune system

Question 1

two types of lymphocytes?

Answer 1

T cell and B cells

Question 2

what do B cells do?

Answer 2

make antibodies

Question 3

principles of clonal selection?

Answer 3

1) Each lymphocyte has a single type of receptor with
a unique specificity.
2) Cells that have receptors specific for self
molecules are deleted from the repertoire.
3) Interaction between a foreign molecule (antigen)
and a lymphocyte receptor capable of binding, leads
to activation of that lymphocyte.
4) The daughter cells derived from an activated cell
have receptors that are identical to those of the
parental cell.

Question 4

what holds together the heavy chains?

Answer 4

disulfide bonds

Question 5

what is the variable region?

Answer 5

light chian

Question 6

what is the constant region?

Answer 6

heavy chain

Question 7

where does antigen bind?

Answer 7

variable region

Question 8

when does somatic hypermutation occur?

Answer 8

occurs in B cells during affinity maturation

Question 9

formation of IgG?

Answer 9

dimer held by J chain

Question 10

formation of IgM?

Answer 10

5 antibody dimers held together by J chain