Block 4: immune system

Question 1

Hydroxocobalamin

Answer 1

Coenzyme
medically supply vitamin B12
Pernicious anaemia

Question 2

Folic acid

Answer 2

DNA precursor

Folate deficiency

Question 3

Ferrous sulphate

Answer 3

oxidation modulator

iron deficiency anaemia

Question 4

Azathioprine

Answer 4

purine synthesis inhibitor
inhibits cell and antibody immune reactions
used in transplant

Question 5

ciclosporine

Answer 5

cyclophilin binder
decreased proliferation of T-cells (decrease IL-2 synthesis) mainly CD8+
used in transplant patients

Question 6

Clopidogrel

Answer 6

ADP antagonist

prevention of atherothrombotic events, also within 35 days MI

Question 7

Heparin

Answer 7

antithrombin 3 activator
inhibits thrombin
DVT and PE ect

Question 8

Lepirudin

Answer 8

irreversible thrombin binder

Thromboembolic disease

Question 9

tetanus booster

Answer 9

antibody stimulator

boosters every 10 years

Question 10

prednisolone

Answer 10

glucocorticoid nuclear receptor agonist

restrain proliferation of CD4 cells (IL-2)

Question 11

Warfarin

Answer 11

Vitamin K antagonist
Anticoagulent
DVT

Question 12

Chlorphenamine

Answer 12

histamine receptor antagonist
Blocks H1 receptors
symptomatic relief of allergy
anaphylaxis

Question 13

Diclofenac

Answer 13

COX inhibitor

pain and inflammation

Question 14

Epinephrine

Answer 14

adrenoreceptor agonist

reverse effects of anaphylaxis

Question 15

Hydrocortisone

Answer 15

glucocorticoid nuclear receptor agonist

hypersensitivity reactions