bleeding disorders

Question 1

most common inherited cause of abnormal bleeding

Answer 1

Von Willebrand Disease

Question 2

genotype of Vwb disease

Answer 2

autosomal dominant

Question 3

cause of vwb disease

Answer 3

deficiency , abscence or malfunctioning of a glycoprotein called Vwf

Question 4

presentation of vwb

Answer 4

bleeding gums with brushing
nose bleeds
heavy periods

Question 5

how is diagnosis of vwb made

Answer 5

through family history and abnormal bleeding

Question 6

management of vwb

Answer 6

no day to day treatment
desmopressin- to stimulate release of vwf
- vwf can be infused
-factor v111 can be infused

Question 7

what is haemophillia

Answer 7

a severe bleeding disorder

Question 8

Haemophillia A is caused by ?

Answer 8

deficiency in factor 8

Question 9

haemophilia B is caused by

Answer 9

deficiency in factor 4

Question 10

genotype of haemophillia

Answer 10

x linked recessive
mostly affects males

Question 11

signs and symptoms of Haemophilia

Answer 11

patients bleed in excess to minor trauma
intercranial haemorrhage
spontaneous bleeding in joints

Question 12

diagnosis for haemophilia is based on

Answer 12

bleeding scores
coagulation factor assays
genetic testing

Question 13

management of haemophilia

Answer 13

• ## clotting factors can be replaced through IV transfusion