bio test 3 Flashcards
basic function of blood/circulation
transport- nutrients, O2/C2, waste
regulation-hormones, temp
protection-antibodies, clotting
components of blood
plasm- H2O, ions, proteins, dissolved elements
cellular- erythrocytes (red BC, O2/C2 transport), leukocytes (white BC, agronulocytes[monocytes-bacteria infection, lymphocytes-antibody production], granulocytes [neutrophils-protects against bacteria, esosinophils-parasitic infections, basophils-inflamation]
platelets-blood clot formation
circulation
fish-single loop
amphibians/reptiles-double circ(pulmonary and systemic)
birds and mammals- 4chamber, doub circ, 2 ventricles, higher metabolism, aerobic resp.
blood vessels-4 layers of arteries, arteiolus, veins, venules
endothelium (inner), elastic fibers, smooth muscle, connective tissues
cappillaries
only endotheliu, permits diffusion, filtration and transport
vasoconstriction/dilation
contriction and opening of capillaries to in/decrease blood flow to specific areas of the body
vein vs. atery
atery-away from heart, high BP, more smooth muscle
vein-toward heart, lower BP, less smooth muscle, one-way values
vericose veins
one-way values don’t function right and blood pools up
respiration
exchange of gas between cells/enviroment, simple diffusion
ficks law of diffusion
diffusion between 2 areas
R=(DxAx[deltaP])/d
fish gills
highly efficient(85% of O2 in H2O), much less O2 in water
respiration in amphibians
cutaneos respiration, positive pressure breathing
respiration in amphibians
negative pressure breathing (thoracic breathing)
human lungs
300,000 alveoli/lung, increase in surface area for diffusion, 2 cell layers thick
bird lungs
2 cycle, unidirectional
eliminate dead airspace
gas exchange in lungs, not airsacs
vertebrate defenses against microbes
general barrier, immunity
general barrier
blocks variety, generic, ex skin or HCl in stomach
immunity
innate-quick recognition and response
adaptive(acquired) immunity ex antibodies
PAMP/MAMP
pathogen/microbe-associated molecule patter
Patter Recognition Receptors
receptors on blood cells or soluble in serum of blood, recognize PAMP’s and MAMP’s
toll-like receptors-TLR produces products that simulate innate and acquired immunity, indirectly triggers inflamation
examples of innate immunity
phagocytic cells(macrophages, neutrophils, natural killer cells) inflammation(up vasodilation, up permeability of capillaries, macrophages release interleukin 1 complement- groups of about 30 inactive proteins, various defense roles
complement proteins
MAC(membrane attack complex)-makes hole in membrane which fuid enters and causes pathogen to burst
C3b-coat surface causing phagocytosis and destruction
adaptive immunity
slow but specific
active-activates lymphocytes
passive-receives antibodies from another source
antigen
any substance that triggers a immune response
epitope
antigenic determinants on some large antigens