Benzodiazepines Flashcards
Benzodiazepines Prototype
Diazepam
Diazepam Indications
Management of anxiety disorders, acute alcohol withdrawal; muscle relaxant, treatment
of tetanus, adjunct in status epilepticus and severe recurrent convulsive seizures, preoperative relief
of anxiety and tension, management of epilepsy in patients who require intermittent use to control bouts of increased seizure activity.
Diazepam Actions
Acts in the limbic system and reticular formation, potentiates the effects of GABA, has little effect on cortical function.
Diazepam Route
Oral, IM, IV, recta
Diazepam Adverse Effects
Drowsiness, sedation, depression, lethargy, apathy, fatigue, disorientation, bradycardia, tachycardia, paradoxical excitatory reactions, constipation, diarrhea, incontinence, urinary retention, drug dependence with withdrawal syndrome.