BC1 Amino Acids and pH

Question 1

Non Polar Amino Acids

Answer 1

Valine (branched hydro)
Alanine (Ch3)
Glycine (H)
Leucine (branched hydro)
Isoleucine (branched hydro)
Proline (Imine) (ring) (can become hydroxylated)
(M T Ph(F))
Phenylalanine (ring)
Tryptophan (Rings & N)
Methionine (S)

Question 2

Polar Uncharged

Answer 2

Glutamine (ONH2)
Serine    (OH) -attachment for P group
Threonine (OH)
Tyrosine (ring-OH)
Cysteine (Sulfer) (Selenocysteine-Se)
Aspargine (ONH2)

Question 3

Charged Acidic

Answer 3

Negative at Phys pH
Glutamic Acid COO-
Aspartic Acid COO-

Question 4

Charged Basic

Answer 4

Positive at Phys pH
Histidine NH1 (not +)
Argenine NH2
Lysine NH3

Question 5

pH & Ka

Answer 5

7.35-7.45 life 6.8-7.8
[H] alter amino acid R groups

Ka (constant)= [H][A]/[HA]

Question 6

Henderson Hasselbalch

Answer 6

pH=pKa+log([A]/[HA])

pH=pKA @ 50/50

pKa = pH +1 pKa-1=pH
91% HA 10% A

Question 7

Buffers

Answer 7

max range, one pH unit above and below pKa

Pulminary Ventilation

• CO2 exhaled, increased of respitory activity reduces acidity of body fluid.
• Renal adjustments, several hours to several days