Bacterial Coverage by Drug Flashcards
Natural Penicillins
Gram positive (streptococci and enterococci, not staphylococci)
Gram positive anaerobes (mouth flora)
Antistaphylococcal Penicillins
MSSA and Streptococci
Aminopenicillins
Gram positive (streptococci and enterococci)
Aminopenicillin with beta lactamase inhibitor covers MSSA
Gram positive anaerobes (mouth flora)
Gram negative (HNPEK)
Gram negative anaerobes (B. fragilis)
Extended-Spectrum Penicillins
Gram positive
Gram negative (HNPEK, CAPES, Pseudomonas)
Gram positive anaerobes
Gram negative anaerobes (B. fragilis)
HNPEK
Haemophilus, Neisseria, Proteus, E. Coli, Klebsiella
CAPES
Citrobacter, Acinetobacter, Providencia, Enterobacter, Serratia
1st Gen. Cephalosporin
Gram positive (staphylococci, streptococci
Preferred cephalosporin for MSSA
Gram negative rods (PEK)
Gram positive anaerobes
2nd Gen. Cephalosporin
Gram positive (staphylococci, streptococci) including MSSA
Gram negative (HNPEK)
Cefotetan and Cefoxitin covers anaerobes
Cefuroxime DOES NOT
3rd Gen. Group 1 Cephalosporin
Resistant streptococci (S. pneumoniae), staphylococci (MSSA)
Resistant gram negative (HNPEK)
Gram positive anaerobes
3rd Gen. Group 2 Cephalosporin
Resistant gram negative (HNPEK)
Pseudomonas
4th Gen. Cephalosporin
Resistant streptococci (S. pneumoniae), staphylococci (MSSA)
Gram negative (HNPEK, CAPES, Pseudomonas)
Gram positive anaerobes
5th Gen. Cephalosporin
Broad Gram positive (no enterococcus b/c cephalosporin; covers MRSA)
Resistant gram negative (HNPEK)
Gram positive anaerobes
Cephalosporin Combinations
Gram positive (staphylococci, streptococci)
Gram negative (HNPEK, CAPES, Pseudomonas)
MDR Gram negative rods (ESB, PEK)
Anaerobes
Avycaz covers CRE
Siderophore Cephalosporins
E. Coli, Enterobacter, Klebsiella, Proteus, Pseudomonas
Carbapenems
Most gram positive (not MRSA)
Most gram negative (including ESBL, HNPEK, CAPES, Pseudomonas)
Anaerobes
Ertapenem does not cover Pseudomonas, Acinetobacter, Enterococcus
Vabomere and Recarbrio covers CRE
Monobactam
Many gram negatives (Pseudomonas and CAPES)