B5-007 GI Infections Flashcards
causes of acute viral gastroenteritis
3
- norovirus
- rotovirus
- adenovirus
non-bloody, non-inflammatory diarrhea
fecal leukocyte negative
acute viral gastroenteritis
“winter vomiting disease”
norovirus
SS RNA, linear, non-enveloped
norovirus
frequently associated with food service workers
norovirus
food service workers should avoid handling food for […] after resolution of symptoms
2 days
at risk populations for norovirus
close quarters
* military
* cruise ships
* dorms
* school age children
can withstand freezing, heating, chlorine, alcohol
norovirus
DS RNA, segmented, nonenveloped
rotavirus
late winter/early spring
peaks in early march
rotavirus
at risk populations for rotavirus
children under 5
particularly 6 mo-2 years
causes villous destruction and atrophy leading to decreased Na+ absorption and loss of K+
rotavirus
who should be vaccinated for rotavirus?
ALL infants except those with hx of intussusception or SCID
is the rotavirus vaccine live attenuated?
yes
DS DNA, linear nonenveloped
adenovirus
which adenovirus serotypes cause gastroenteritis?
40, 41
other clinical manifestations include conjunctivitis, upper and lower RTIs, and hemmorhagic cystis
adenovirus
which populations are at risk for adenovirus?
children
which protozoa covered is not free living?
trichomonas
eosinophilia absent indicates..
protozoal infection
active feeding forms of protozoa
trophozoites
environmentally resistant forms of protozoa
cysts
preferred method of diagnosis for giardia and cryptosporidium
stool antigen (ELISA)
what diagnostic test may be useful for entamoeba?
serum antibody
pretty much useless for anything else though
- bloody diarrhea
- RUQ pain
- anchovy paste liver abscess
name the protozoa!
entamoeba histolytica
flask shaped ulcer on colon biopsy
name the protozoa!
entamoeba histolytica
entamoeba eats […]
erythrocytes
trophozoites ingest RBCs
treatment for entamoeba histolytica
metronidazole
(asymptomatic cyst passers: paromomycin, idoquinol
pregnancy: paromomycin)
aka Beaver Fever due to association with campers/hikers drinking freshwater
giardia lamblia
- bloating
- flatulence
- foul smelling, fatty, non-bloody diarrhea
giardia lamblia
ghirardelli makes me fat = giardia fatty diarrhea
treatment for giardia lamblia
metronidazole
in immunocompetent hosts, presents with mild watery diarrhea
but in AIDS patients presents with severe diarrhea with wasting
cryptosporidium
associated outbreaks with pools and water parks, daycares
cryptosporidium