B.21 Drosophila AD Flashcards

1
Q

Advantages of Drosophila Model in Neurodegeneration

A
  • cheap
  • easy to handle
  • high n number possible
  • genetically similar to human (65% of genes preserved)
  • quick generation cycle
  • short life span
  • replicate disease
  • cellular mechanisms conserved
  • similarity in protein structure and function in neurodegeneration
  • only 4 chromosomes so genome fully sequenced
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