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Second Year Need-to-Knows > Autoimmune Antibodies > Flashcards

Autoimmune Antibodies Flashcards

1
Q

anti-CCP

A

rheumatoid arthritis

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2
Q

rheumatoid factor

A

seropositive arthritides

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3
Q

anti-dsDNA

A

systemic lupus erythematosus

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4
Q

anti-Sm

A

systemic lupus erythematosus

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5
Q

anti-Ro/anti-La

A

Sjorgen’s syndrome

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6
Q

anti-centromere

A

limited systemic sclerosis (CREST)

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7
Q

anti-Scl-70

A

diffuse systemic sclerosis

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8
Q

anti-GAD

A

diabetes mellitus

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9
Q

cANCA

A

GPA (Wegener’s).

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10
Q

pANCA

A

MPA, EGPA

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11
Q

what substance is cANCA directed at?

A

PR3

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12
Q

what substance is pANCA directed at?

A

MPO

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13
Q

anti-RNP

A

SLE, mixed connective tissue disease (MCTD)

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14
Q

anti-Jo-1

A

myositis (inflammatory myopathies)

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15
Q

anti-cardiolipin

A

anti-phospholipid syndrome

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16
Q

lupus anti-coagulant

A

anti-phospholipid syndrome

17
Q

ANA

A

SLE, Sjorgen’s, systemic sclerosis, MCTD, autoimmune liver disease (i.e. not very specific)

18
Q

anti-beta 2 glycoprotein

A

anti-phospholipid syndrome

19
Q

anti-SRP

A

myositis (inflammatory myopathies)

20
Q

myositis (inflammatory myopathies)

A

anti-Jo-1, anti-SRP

21
Q

anti-phospholipid syndrome

A

lupus anti-coagulant, anti-cardiolipin, anti-beta 2 glycoprotein

22
Q

SLE, Sjorgen’s, systemic sclerosis, MCTD, autoimmune liver disease (i.e. not very specific)

23
Q

SLE

A

ANA, anti-RNP, anti-Sm, anti-dsDNA

24
Q

what antibody is directed against PR3?

25
what antibody is directed against MPO?
pANCA
26
cANCA
GPA (Wegener's)
27
pANCA
MPA, EGPA (Churg-Strauss)
28
diabetes mellitus
anti-GAD
29
diffuse systemic sclerosis
anti-Scl-70
30
limited systemic sclerosis
anti-centromere
31
Sjorgen's syndrome
ANA, anti-Ro, anti-La
32
MCTD
ANA, anti-RNP
33
seropositive arthritides
rheumatoid factor
34
rheumatoid arthritis
rheumatoid factor, anti-CCP

Second Year Need-to-Knows (5 decks)

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