Autoimmune and HIV

Question 1

Autoimmune diseases Circulating antibodies ANA Abnormal Titer - 1/40 or 1/80

Answer 1

Connective Tissue Disease

Question 2

1/160 Titer

Answer 2

NOT diagnostic.

Question 3

Acute QT Subacute QT Chronic QT

Answer 3

Lupus Erythematous Variants Anti-histone antibodies

Question 4

Butterfly rash Anti-DsDNA

Answer 4

Acute cutaneous lupus

Question 5

V of neck rash Extensors Annular/polycyclic plaques Anti-Ro

Answer 5

Subacute cutaneous lupus

Question 6

Early lesions are well demarcated and scale/scar Late lesions occur with atrophic plaques, central scarring and telangiectasia

Answer 6

Chronic cutaneous lupus

Question 7

15x more common in women, endothelial damage is suspected pathology

Answer 7

Scleroderma

Question 8

Sclerodactylyl, Raynaud’s with hyperpigmentation Anti-Scl-70

Answer 8

Systemic Scleroderma

Question 9

Plaque - sclerotic and scar-like Deep - deep tissue necrosis En coupe de saber - linear on forhead/scalp Anti-fibrillin-1

Answer 9

Morphea

Question 10

What is CREST?

Answer 10

Calcinosis cutis Raynaud’s Esophageal dysfunction Sclerodactyly Telangiectasia

Question 11

Anti-centrome

Answer 11

CREST Syndrome

Question 12

Proximal extensor inflammatory myopathy.

Answer 12

Dermatomyositis/Polymyositis

Question 13

Gottron’s papules/Gottron’s sign

Answer 13

Cutaneous DM/PM

Question 14

Proximal muscle weakness and pulmonary fibrosis Anti-Jo1

Answer 14

Systemic DM/PM

Question 15

Females in their 30/40s, sausage fingers, synovitis, myositis, Raynaud’s, and acrosclerosis Anti-RNP

Answer 15

MCTD

Question 16

Inflammation of cartilaginous tissue, ears Recurrent articular chondritis, cochlear and vestibular damage Increased ESR and antibodies to type II collagen

Answer 16

Relapsing polychondritis

Question 17

MOST common infection in the early stage of HIV Malassezia furfur Erythema with greasy scaling

Answer 17

Seborrheic dermatitis

Question 18

Often caused by immune dysregulation

Answer 18

Psoriasis

Question 19

Mononucleosis-like illness with fever. Maculopapular rash with oral and genital ulcers

Answer 19

Xanthem

Question 20

Group A strep MOST commonly staph aureus

Answer 20

Type I HIV

Question 21

Extensive infections such as CMV and HPV

Answer 21

Type II HIV

Question 22

Opportunistic infections such as fungal, mycobacteria, and Pneumocystis jiroveci

Answer 22

Type III HIV

Question 23

Metastatic infections from systemic diseases

Answer 23

Type IV HIV

Question 24

Infections specific to AIDS such as oral hairy leukoplakia and Kaposi’s

Answer 24

Type V HIV

Question 25

Red/brown flat macules caused by HHV8 that presents with originally as violaceous macules that ulcerate and diffusely infiltrate.

Answer 25

Kaposi’s Sarcoma