atherosclerosis

Question 1

what does Is the development of atherosclerosis?

Answer 1

injury to the endothelium

Question 2

what can cause atherosclerosis?

Answer 2

HTN, chemicals in cigarette smoke, infectious agents, and shear forces of blood

Question 3

what can atherosclerosis lead to?

Answer 3

HTN, CAD, cerebrovascular accident, peripheral artery disease

Question 4

what are the stages of atherosclerosis

Answer 4

fatty streak
fibrinous plaque
complicated lesion

Question 5

fatty streak:

Answer 5

Endothelial damage is followed by migration of macrophages and smooth muscle cells (SMC) into the endothelium. macrophages release free radials that steal electrons from LDL’s. LDL’s then can move into the vessel. Both macrophages and SMCs ingest low density lipoproteins (LDLs). Macrophages and SMCs become foam cells once they’ve ingested the LDLs

Question 6

fibrinous plaque:

Answer 6

collagen fibers are laid down forming a cap of fibrous tissue. and the plaque grows. Vessels become further obstructed.