Anxiety and Depression Case Study Flashcards
How common is mirtazapine in increasing weight ?
Vey common 1/10
True or false. Flucoxetine causes weight increase as an uncommon side effect
False, weight decrease is a commonly reported adverse reaction
True or false. Weight gain with paroxetine is a rarely reported side effect ?
Weight gain is commonly reported adverse reaction
True or false. Amitriptyline is not associated with weight gain
False. weight increase is very commonly reported adverse reaction
Duloxetine tends to cause weight decrease more often than weight increase ?
True, weight decrease is a commonly reported adverse reaction with duxetine whereas weight increase is an uncommonly reported adverse effect
The tricyclic antidepressants (TCADs) tend to be more sedative than the serotonin and noradrenaline re-uptake inhibitors (SNRIs) and as a result of this, cause similar impacts on bodyweight
True, tricyclic antidepressants (e.g. amitriptyline) are generally more sedative than the SNRI antidepressants (e.g. duloxetine) and tend to cause more weight gain as a result.
Give an example of a TCAD
Amitriptyline
True or false. The greater an antidepressants affinity for blocking the histamine H1 receptor the greater the risk of the antidepressant causing weight gain.
Correct, histamine H1 antagonism is associated with sedation and sedative antidepressants (e.g. mirtazapine and TCADs) with potent antihistaminergic properties tend to cause more weight gain than less sedative antidepressants (e.g. SSRIs and SNRIs).
Why is paroxetine more likely to cause withdrawal symptoms than fluoxetine ?
Paroxetine is excreted from the human body significantly faster than fluoxetine
What is a panic attack ?
A panic attack is a sudden and intense episode of anxiety and fear that can be very frightening and distressing. A panic attack usually lasts 5-30 minutes, sometimes up to an hour. They are not dangerous and should not cause any physical harm.
What is a panic disorder ad when is it likely to be diagnosed ?
Panic disorder is likely to be diagnosed if a person has regular and unexpected panic attacks followed by at least a month of continuous worry or concern about having further attacks.
What are the treatment options for a panic attack ?
Cognitive behavioural therapy
Sertraline
What antidepressants are licensed fro the treatment of panic disorders ?
citalopram, escitalopram, paroxetine, sertraline and venlafaxine. The initial recommended doses of these antidepressants for panic disorder are different from the starting doses recommended for depressive illness.
