Antiplatelet and Thrombolytics

Question 1

Why is pragsugrel better than clopidogrel in some patients?

Answer 1

Patients with CYP2C19 mutations should be given prasugrel because these mutations effect the metabolism of clopidogrel

Question 2

Why would a thrombolytic not be given to a patient with thrombosis?

Answer 2

If they have unmanaged bleeding.

Question 3

What type of dosing does streptokinase require? why?

Answer 3

ONE-TIME dosing. Creating strong immune response and won’t be affective the second time, and can cause serum sickness if antibodies attack it.