antiparkansonian

Question 1

direct acting dopamine receptor agonists MOA

Answer 1

direct stimulation of dopamine receptors in the brain

Question 2

direct acting dopamine receptor agonists

Answer 2

bromocriptine

Question 3

dopamine replacement drugs MOA

Answer 3

biological precursor of dopamine that is able to cross the blood brain barrier

Question 4

dopamine replacement drugs example

Answer 4

levadopa

Question 5

what is levodopa used with

Answer 5

carbidopa

Question 6

carbidopa MOA

Answer 6

does not cross the blood brain barrier, but prevents levadopa breaking down in the periphery for more of it to be used

Question 7

how does levadopa get into the brain

Answer 7

taken up by dopaminergic terminal then is converted to dopamine and used as needed

Question 8

selective MOAI therapy mechanism of action

Answer 8

inhibit MOA, which breaks down catecholamines in the brain

Question 9

selective MAOI therapy drugs

Answer 9

selegiline and rasagiline

Question 10

dopamine modulator drug example

Answer 10

amantadine

Question 11

dopamine modulator MOA

Answer 11

causes release of dopamine and catecholamines from storage sites, blocks the retake of dopamine

Question 12

COMT inhibitor mechanism of action

Answer 12

block COMT, which breaks down catecholamines

Question 13

COMT inhibitors example

Answer 13

entacapone

Question 14

anticholinergic therapy MOA

Answer 14

treats muscle tremors and ridgety caused by excessive cholinergic activity

Question 15

antcholenergic therapy drug example

Answer 15

benztropine