Antineoplastic Agents: Drug Categories

Question 1

1. Antimetabolites

(8)

Answer 1

Methotrexate

5-fluorouracil (5-FU)

Cytarabine

Gemcitabine

6-Thioguanine (6-TG)

6-Mercaptopurine (6-MP)

Fludarabine

Cladribine

Question 2

2. Common Alkylating Agents

(3)

Answer 2

Cyclophosphamide

Carmustine (BCNU)

Mechlorethamine

Question 3

3. Non-Classical Alkylating Agents

(6)

Answer 3

Cisplatin (1st Gen)

Carboplatin (2nd Gen)

Oxaliplatin (3rd Gen)

Procarbazine

Dacarbazine

Temozolomide

Question 4

4. Plant Derivatives and Similar Agents

(6)

Answer 4

Vinblastine

Vincristine

Paclitaxel

Irinotecan

Topotecan

Etoposide

Question 5

5. Cytotoxic Antibiotics

(2)

Answer 5

Doxorubicin

Bleomycin

Question 6

6. Targeted Therapies

(16)

(e.g. Hormones and Related Agents, Monoclonal Antibodies, Small Molecule Kinase Inhibitors, Miscellaneous)

Answer 6

Glucocorticoids

Tamoxifen

Anastrozole

Flutamide

Leuprolide

Goserelin

Degarelix

Trastuzumab

Cetuximab

Bevacizumab

Lapatinib

Erlotinib

Imatinib

Asparaginase

Bortezomib

Temsirolimus