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Microbiology > Antimicrobials > Flashcards

Antimicrobials Flashcards

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0
Q

Methcillin

A

Block cell wall synthesis by inhibition of peptidoglycan cross linking.

S. Aureus

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1
Q

Penicillin

A

Block cell wall synthesis by inhibition of peptidoglycan cross linking.

Bind PBP

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2
Q

Ampicillin

A

Block cell wall synthesis by inhibition of peptidoglycan cross linking.

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3
Q

Piperacillin

A

Block cell wall synthesis by inhibition of peptidoglycan cross linking.

Anti pseudomonal (ticeracillin, carbenucillin)

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4
Q

Cephalosporins

A

Block cell wall synthesis by inhibition of peptidoglycan cross linking.

Not covered - Listeria, Atypicals ( chlam, mycoplasma), MRSA, Enterococci

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5
Q

Aztreotam

A

Block cell wall synthesis by inhibition of peptidoglycan cross linking.

Bind PBP3

B lac resistant

G- only

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6
Q

Imipenem

A

Block cell wall synthesis by inhibition of peptidoglycan cross linking.

B lac resistant

Use with cilastin

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7
Q

Vancomycin

A

Block peptidoglycan synthesis

Bind D-ala-ala

G+ only

Ototox

Pretreat with anti histamine

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8
Q

Bacitracin

A

Block peptidoglycan synthesis

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9
Q

Sulfonamides

A

Block nucleotide synthesis

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10
Q

Trimethoprim

A

Block nucleotide synthesis

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11
Q

Fluoroquinolones

A

Block topoisomerase II

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12
Q

Rifampin

A

Block mRNA synthesis

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13
Q

Metronidazole

A

damage DNA

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14
Q

Chloramphenicol

A

Block 50s subunit

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15
Q

Macrolides (erythromycin)

A

Block 50s subunit

16
Q

Clindamycin

A

Block 50s subunit

17
Q

Streptogamin (quinupristin, dalfoprustin)

A

Block 50s subunit

18
Q

Linezolid

A

Block 50s subunit

19
Q

Aminoglycosides (gentamicin, neomycin, amikacin, tobramycin, streptomycin)

A

Inhibit 30s subunit

20
Q

Tetracyclines

A

Inhibit 30s subunit

Microbiology (3 decks)

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