Antihistamines, NSAIDs, GI Flashcards

1
Q

Sodium bicarbonate

A

Acid-neutralizing agent

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2
Q

Calcium carbonate

A

Acid-neutralizing agent

TUMS

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3
Q

Magnesium hydroxide/ Aluminum hydroxide

A

Acid-neutralizing agent

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4
Q

“Tidines”

A

H2 Histamine Antagonist

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5
Q

Cimetidine

A

H2 Histamine Antagonist

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6
Q

Ranitidine

A

H2 Histamine Antagonist

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7
Q

Famotidine

A

H2 Histamine Antagonist

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8
Q

Nizatidine

A

H2 Histamine Antagonist

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9
Q

“Prazoles”

A

PPIs

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10
Q

Omeprazole

A

PPI

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11
Q

Esomeprazole

A

PPI

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12
Q

Lansoprazole

A

PPI

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13
Q

Rabeprazole

A

PPI

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14
Q

Pantoprazole

A

PPI

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15
Q

Misoprostol

A

Cytoprotective agent

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16
Q

Bismuth subsalicylate

A

Cytoprotective agent

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17
Q

Metoclopramide

A

Prokinetic agent

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18
Q

Bethanechol

A

Prokinetic agent

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19
Q

Erythromycin

A

Prokinetic agent

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20
Q

Dicyclomine

A

Antispasmotic for IBS

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21
Q

Amitriptyline

A

Antispasmotic for IBS

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22
Q

Eluxadoline

A

Antispasmotic for IBS

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23
Q

Glycopyrrolate

A

Antispasmotic for IBS

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24
Q

Ondasetron

A

Anti-nausea
Anti-emetic
Serotonin (5HT3)
antagonist

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25
Q

“setrons”

A

Anti-nausea
Anti-emetic
Serotonin (5HT3) antagonist

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26
Q

Granisetron

A

Anti-nausea
Anti-emetic
Serotonin (5HT3)
antagonist

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27
Q

Palonosetron

A

Anti-nausea
Anti-emetic
Serotonin (5HT3) antagonist

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28
Q

Dolasetron

A

Anti-nausea
Anti-emetic
Serotonin (5HT3) antagonist

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29
Q

Promethazine

A

Anti-nausea

Anti-emetic

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30
Q

Prochlorperazine

A

Anti-nausea

Anti-emetic

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31
Q

Dronabinol

A

Anti-nausea

Anti-emetic

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32
Q

Aprepitant

A

Anti-nausea

Anti-emetic

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33
Q

Loperamide

A

Antidiarrheal

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34
Q

Diphenoxylate + atropine

A

Lomotil

Antidiarrhea

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35
Q

Simethicone

A

Gas-X

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36
Q

Sulfasalazine

A

Anti-inflammatory

DMARD

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37
Q

Infliximab

A

Anti-inflammatory

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38
Q

Adalimumab

A

Anti-inflammatory

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39
Q

Methylcellulose

A

Bulk laxative

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40
Q

Psyllium

A

Bulk laxative

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41
Q

Carboxymethylcellulose

A

Bulk laxative

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42
Q

Magnesium hydroxide

A

Osmotic laxative

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43
Q

Sodium salts

A

Osmotic laxative

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44
Q

Lactulose

A

Osmotic laxative

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45
Q

Sorbitol

A

Osmotic laxative

Sweetener

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46
Q

Mannitol

A

Osmotic laxative

Sweetener

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47
Q

Polyethylene glycol

A

Osmotic laxative

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48
Q

Mineral oil

A

Laxative, lubricating agent

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49
Q

Docusate sodium

A

Laxative, lubricating agent

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50
Q

Glycerin suppositories

A

Laxative, lubricating agent

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51
Q

Lubiprostone

A

Prostaglandin E1 derivative

Used to treat constipation

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52
Q

Linaclotide

A

indirectly activates CFTR (increased Cl- secretion)

Used to treat constipation

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53
Q

Castor oil

A

Laxative, lubricating agent

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54
Q

Diphenhydramine

A

Very sedating first generation H1 antagonist

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55
Q

Dimenhydrinate

A

Very sedating first generation H1 antagonist

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56
Q

Doxylamine

A

Very sedating first generation H1 antagonist

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57
Q

Promethazine

A

Very sedating first generation H1 antagonist

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58
Q

Hydroxyzine

A

Very sedating first generation H1 antagonist

59
Q

Brompheniramine maleate

A

Moderately sedating first generation H1 antagonist

60
Q

Chlorpheniramine maleate

A

Moderately sedating first generation H1 antagonist

61
Q

Clemastine

A

Moderately sedating first generation H1 antagonist

62
Q

Cyclizine

A

Moderately sedating first generation H1 antagonist

63
Q

Meclizine

A

Moderately sedating first generation H1 antagonist

64
Q

Loratadine

A

Second generation H1 antagonist

65
Q

Desloratadine

A

Second generation H1 antagonist

66
Q

Cetirizine

A

Second generation H1 antagonist

67
Q

Levocetirizine

A

Second generation H1 antagonist

68
Q

Acrivistine/Pseudoephedrine

A

Second generation H1 antagonist

69
Q

Fexofenadine

A

Second generation H1 antagonist

70
Q

Azelastine

A

Nasal H1 antagonist

71
Q

Levocabastine

A

Nasal H1 antagonist

72
Q

Albuterol

A

Short acting B2 agonist (SABA)

73
Q

Levalabuterol

A

Short acting B2 agonist (SABA)

74
Q

Pirbuterol

A

Short acting B2 agonist (SABA)

75
Q

Terbutaline

A

Short acting B2 agonist (SABA)

76
Q

Salmeterol

A

Long acting B2 agonist (LABA)

77
Q

Salmeterol/fluticasone

A

Long acting B2 agonist (LABA)
+
Inhaled Corticosteroid

78
Q

Formoterol

A

Long acting B2 agonist (LABA)

79
Q

Formoterol/mometasone

A

Long acting B2 agonist (LABA)
+
Inhaled corticosteroid

80
Q

Formoterol/budesonide

A

Long acting B2 agonist (LABA)
+
Inhaled corticosteroid

81
Q

Vilanterol/Fluticasone

A

Long acting B2 agonist (LABA)
+
Inhaled corticosteroid

82
Q

Fluticasone

A

Inhaled corticosteroid

83
Q

Beclomethasone

A

Inhaled corticosteroid

84
Q

Flunisolide

A

Inhaled corticosteroid

85
Q

Montelukast

A

Leukotriene inhibitor

86
Q

Zafirlukast

A

Leukotriene inhibitor

87
Q

Zileuton

A

Leukotriene inhibitor

88
Q

Omalizumab

A

IgE monoclonal antibody for asthma

89
Q

Benralizumab

A

IL-5 monoclonal antibody for eosinophilic asthma

90
Q

Cromolyn sodium

A

For asthma: Inhibits release of histamine from mast cells

91
Q

Mepolizumab

A

IL-5 monoclonal antibody for eosinophilic asthma

92
Q

Reslizumab

A

IL-5 monoclonal antibody for eosinophilic asthma

93
Q

Methyl salicylate (oil of winter green)

A

Salicylate

94
Q

Celecoxib

A

COX-2 inhibitor

95
Q

Indomethacin

A

Nonspecific COX inhibitor

96
Q

Sulindac

A

Nonspecific COX inhibitor

97
Q

Aspirin

A

Irreversible COX 1 + 2 inhibitor

98
Q

Diclofenac

A

Nonspecific COX inhibitor

99
Q

Ketorolac

A

Nonspecific COX inhibitor

100
Q

Ibuprofen

A

Nonspecific COX inhibitor

101
Q

Naproxen

A

Nonspecific COX inhibitor

102
Q

Piroxicam

A

Nonspecific COX inhibitor

103
Q

Meloxicam

A

Nonspecific COX inhibitor

104
Q

Arthrotec

A

Diclofenac + Misoprostol

105
Q

Acetaminophen

A

Nonspecific COX inhibitor

106
Q

Phenylbutazone

A

Very potent NSAID, not available in US due to toxicities

107
Q

Aurothioglucose

A

DMARD

Gold salt

108
Q

Auranofin

A

DMARD

Gold salt

109
Q

Gold Sodium Thiomalate

A

DMARD

Gold salt

110
Q

Penicillamine

A

DMARD

Chelating agent

111
Q

Hydroxychloroquine sulfate

A

DMARD

112
Q

Infliximab

A

DMARD

Anti-TNF alpha drug

113
Q

Adalimumab

A

DMARD

Anti-TNF alpha drug

114
Q

Certolizumab

A

DMARD

Anti-TNF alpha drug

115
Q

Golimumab

A

DMARD

Anti-TNF alpha drug

116
Q

Etanercept

A

DMARD

Anti-TNF alpha drug

117
Q

Rituximab

A

DMARD

Inhibitor of B cell differentiation and T cell activation

118
Q

Abatacept

A

DMARD

Inhibitor of B cell differentiation and T cell activation

119
Q

Anakinra

A

DMARD

Interleukin receptor antagonist

120
Q

Tocilizumab

A

DMARD

Interleukin receptor antagonist

121
Q

Leflunomide

A

DMARD

Inhibitor of nucleic acid synthesis

122
Q

Mycophenolate mofetil

A

DMARD

Inhibitor of nucleic acid synthesis

123
Q

Tofacitinib

A

JAK inhibitor

124
Q

Baricitinib

A

JAK inhibitor

125
Q

“citinib”

A

JAK inhibitor

126
Q

“ximab”

A

X=crossed=chimeric monoclonal antibody

Human + murine

127
Q

“mumab”

A

human monoclonal antibody

128
Q

“zumab”

A

humanized monoclonal antibody

129
Q

“cept”

A

Fusion proteins that “block/intercept” certain pathways

NOT a monoclonal antibody

130
Q

“triptans”

A

5HTD agonists

131
Q

Sumatriptan

A

5HTD agonist

132
Q

Rizatriptan

A

5HTD agonist

133
Q

Naratriptan

A

5HTD agonist

134
Q

Zolmitriptan

A

5HTD agonist

135
Q

Eletriptan

A

5HTD agonist

136
Q

Frovatriptan

A

5HTD agonist

137
Q

Ergotamine

A

Acts on 5-HT receptors

138
Q

Dihydroergotamine

A

Acts on 5-HT receptors

139
Q

Colchicine

A

Alkaloid, anti-inflammatory only effect for gout

140
Q

Allopurinol

A

Xanthine oxidase inhibitor

141
Q

Febuxostat

A

Xanthine oxidase inhibitor

142
Q

Rasburicase

A

Enzyme that converts uric acid to allantoin

143
Q

Pegloticase

A

Enzyme that converts uric acid to allantoin

144
Q

Lesinurad

A

URAT1 inhibitor