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farma > Antigotosos > Flashcards

Antigotosos Flashcards

1
Q

1 en gota aguda

A

Colchicina

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2
Q

EA de colchicina

A

Diarrea en agua de arroz, nausea, vomito y dolor abdominal.

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3
Q

Suprime formación de leucotrieno B4

Alivia dolor e inflamación de artritis gotosa en 12-24h.

A

Colchicina

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4
Q

Tx #1 para gota crónica entre crisis agudas

A

Alopurinol

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5
Q

Mecanismo de acción del alopurinol

A

Inhibe xantina oxidasa

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6
Q

En qué px se utiliza el alopurinol

A

Px con ca hematologico sometidos a quimio

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7
Q

Mecanismo de acción de Febuxostat

A

Inhibe a xantina oxidasa

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8
Q

Tx de hiperuricemia crónica

A

Febuxostat

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9
Q

Indicado en pediatricos con leucemia, linforma y tumores en tx antineoplasico

A

Rasburicasa

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10
Q

Mecanismo de acción de Rasburicasa

A

Cataliza oxidación de ácido urico a alantoina

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11
Q

EA de Rasburicasa

A

Hemolisis en deficiencia de G6FD

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12
Q

Fármaco uricosurico que inhibe URAT-1 en el cual es indispensable mantener gran volumen urinario

A

Probenecid

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13
Q

Indicado en secreción inadecuada de ácido urico en gota cuando alopurinol y Febuxostat están CI o hay TOFOS

A

Probenecid

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14
Q

EA del probenecid

A

Litiasis renal y Sx nefrotico

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15
Q

El probenecid reduce su acción si al mismo tiempo se le da:

A

Salicilatos

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16
Q

Disminuye reserva corporal de urato en px con GOTA TOFACEA o CRISIS DE GOTA

A

Sulfinpirazona

17
Q

Inhibe URAT-1

Eficiente en px con insuficiencia renal

A

Benzbromarona

18
Q

EA de Benzbromarona

A

Nefrolitiasis y hepatotoxico

19
Q

Mecanismo de acción de los AINES en px con gota

A

Inhibir síntesis de prostaglandinas, inhiben fagocitosis de cristales de urato

20
Q

AINES utilizados en gota

A

Indometacina
Sulindaco
Oxaprozina

21
Q

Tx de gota crónica que no responde a otros tx

A

Pegloticasa

22
Q

Mecanismo de acción de Pegloticasa

A

Cataliza oxidación de ácido urico en alantoina

farma (16 decks)

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