Antidepressants Flashcards
Citalopram
Celexa; SSRI
Anxiety, depression
Escitalopram
Lexapro; SSRI
Anxiety, depression
Fluoxetine
Prozac; SSRI
Anxiety, depression
Paroxetine
Paxil; SSRI
Anxiety, depression
Sertraline
Zoloft; SSRI
Anxiety, depression
Desvenlafaxine
Pristiq; SNRI
Depression
Duloxetine
Cymbalta; SNRI
Anxiety, depression
Venlafaxine
Effexor; SNRI
Anxiety, depression
Amitriptyline
Elavil; tricyclic antidepressant
Anxiety, depression, insomnia
Doxepin
Sinequan; tricyclic antidepressant
Anxiety, depression, insomnia
Nortriptyline
Pamelor; tricyclic antidepressant
Anxiety, depression
Phenelzine
Nardil; monoamine oxidase inhibitor
Anxiety, depression
Selegiline
Eldepryl; monoamine oxidase inhibitor
Depression
Bupropion
Wellbutrin; misc antidepressant
Depression, smoking cessation
Mirtazapine
Remeron; misc antidepressant
Depression
Vortioxetine
Trintellix; misc antidepressant
Depression
Trazodone
Desyrel; misc antidepressant
Depression, anxiety, insomnia
Antidepressants have a boxed warning for…
Potential suicidal ideation, especially for kids and teens taking antidepressant
Tricyclic antidepressants (TCAs) are known to cause these adverse reactions: (4)
Constipation, drowsiness, dry mouth, blurry vision (anticholinergic effects)
These side effects are common with antidepressants due to an increase of serotonin in the bloodstream/body (4)
Nausea, vomiting, GI issues, sexual dysfunction
Adverse side effects for antidepressants (5)
Sexual dysfunction, insomnia, drowsiness, weight gain or loss, GI issues
Antidepressants can interact with other serotonergic meds, causing this condition that can be fatal in rare cases
Serotonin syndrome
Serotonin syndrome consists of various symptoms…
Tremor, restlessness, fever, flushing, diarrhea, sweating, blood pressure changes, mental status changes
In rare cases, can be fatal
Aged cheese, wine, and other tyramine-containing foods interact with this class…
MAOIs; causes severe hypertension and can be fatal
Phenelzine (Nardil), selegiline (Elepryl)
Bupropion should be avoided in patients with this disorder, or at risk for this disorder (ex. anorexic patients)
Seizures
Some antidepressants are on the Beers list due to these adverse reactions… (2)
Increased fall risk, increase risk for dementia and cognitive impairment
This antidepressant should be taken in the morning, due to the potential for causing insomnia if taken at night
Fluoxetine (Prozac)
Antidepressants should be avoided with this substance due to the risk of CNS depression
Alcohol
St John’s Wort
A flowering plant used as a natural treatment for depression, but can cause serotonin syndrome if used with other antidepressants
Antidepressants can take as long as __________ to take effect, so it is important to adhere to the medication
8 weeks
Two meds that can interact with antidepressants and cause serotonin syndrome
Tramadol, methadone