ANTIDEPRESSANTS

Question 1

Classifications of Antidepressants

Answer 1

SSRIs - Selective Seroton reuptake inhibitor)

SNRI/DNRI - Serotonin norepinephrine/ Dopaminr Norepinephrine Reuptake Inhibitor

TCA - Tricyclic Antidepressants

MAOI’s - Monoamine axidase inhibitor

Question 2

SSRI mode of action

Answer 2

Inhibits UPTAKE OF SEROTONIN (Increased serotonin)

Question 3

Uses of SSRI (4)

Answer 3

Depression, anxiety, OCD, Eating disorder

Question 4

Side effects of SSRI in neuro

Answer 4

Headache, tremors, difficulty sleeping

Question 5

Side effects of SSRI in GI

Answer 5

Nausea, dry mouth, thirst, constipation, urinary retention, sexual dysfunction

Question 6

3s of SSRI

Answer 6

SEROTONIN Syndrome

SEXUAL Dysfunction

Stomach Issues

Question 7

Too much serotonin in brain is called?

Answer 7

Serotonin syndrome

Question 8

Descriptions for serotonin syndrome (6)

Answer 8

• too much serotonin in brain
• mental changes
• tachycardia
• tightness in muscle
• difficulty walking
• increase temp and bp

Question 9

How SSRIs are administered to px?

Answer 9

Administered with meals

Question 10

How many weeks gap should SSRI be administered before giving MAOIs and TCA?

Answer 10

5 weeks

Question 11

After giving TCA/MAOIs, after how many weeks will it take before givimg SSRI?

Answer 11

2 weeks

Question 12

How many weeks for SSRI to take and effect?

Answer 12

4-6 weeks

Question 13

When should SSRIs be taken?

Answer 13

In the morning

Question 14

SSRIs is the?

Answer 14

First line drug for anxiety and depression

Question 15

What should we educate to px taking SSRIs?

Answer 15

Importance of compliance

Question 16

What will happen to px with suicid plans?

Answer 16

Have the energy due to meds to carry out plan

Question 17

Generic drugs for SSRI (5)

Answer 17

Sertraline
Citalopram
Escitalopram
Fluoxetine
Vilazodone

Question 18

Trade name for sertraline

Answer 18

Zoloft

Question 19

Trade name fir citalopram

Answer 19

Celexa

Question 20

Trade name for escilatopram

Answer 20

Lexapro

Question 21

Trade name for fluoxetine

Answer 21

Prozac

Question 22

Trade name for Vilazodonr

Answer 22

Vibryd

Question 23

Suffixes used in SSRIs (3)

Answer 23

• talopram
• oxetine
  -zodone

Question 24

It affects serotonin norepinephrine and dopamin (classification of antidepressants)

Answer 24

SNRI/DNRI

Question 25

Uses of SNRI (4)

Answer 25

-Depresive episodes
-anxiety disorder
-fibromyalgia
- diabetic neuropathy pain

Question 26

Side effects of SNRI Un neuro (7)

Answer 26

• headache
  -dizziness
  -vertigo
• photosensitivity
  -agitation
  -tremors
  -insomnia

Question 27

Side effects of SNRI/DNRI in GI (6)

Answer 27

• dry mouth
• thirst
• dehydration
• constipation
• nausea
• diarrhea

Question 28

How many werks does SNRI/DNRI to take an effect?

Answer 28

4-6 weeks

Question 29

SNRI should not mix with?

Answer 29

TCA, MAOI

Question 30

Drug used for smiking cessation

Answer 30

Zyban

Question 31

Zyban should NOT use while taking? (Drug)

Answer 31

Bupropion

Question 32

Why zyban should bot use while taking bupropion?

Answer 32

Can cause OVERDOSE

Question 33

Generic drugs under SNRI (5)

Answer 33

• bupropion
• duloxetube
  -veniafaxine
• milnacipran
• nefazodone

Question 34

Bupropion trade name

Answer 34

Zyban & Wellbutrin

Question 35

Duloxetine trade name

Answer 35

Cymbalta

Question 36

Veniafaxine trade name

Answer 36

Effexor XR

Question 37

Milnacipran trade name

Answer 37

Savella

Question 38

Suffixes of drugs for SNRI (3)

Answer 38

• faxine
  -zodone
  -nacipram