Anti-Thrombotic Therapy: Cases Flashcards
Antithrombotic Agents include:
- Aspirin
- P2Y12 Inhibs
- Glycoprotein IIb/IIIa Inhibs
- Fibrinolytics
- Oral Anticoagulants
- Vitamin K Antagonist
- IV/Sq Anticoagulants
Name P2Y12 Inhibs
Prasugrel
Clopidogrel
Ticagrelor
Name Glycoprotein IIb/IIIa Inhibs
Abciximab
Tirofiban
Eptifibatide
Name Fibrinolytics
Streptokinase
t-PA
Urokinase
Name Vitamin K Antagonist
Warfarin
Name IV/SQ Anticoagulants
Heparin
Fondaparinux
Enoxaparin
Bivalirudin
Name Oral Anticoagulants
Apixaban
Rivaroxaban
Dabigatran
Initial drug therapy for Acute Coronary Syndrome
Aspirin
PCT
Heparin, Enoxaparin
Prasugrel is contraindicated in
patients with prior stroke
Preferred P2Y12 Inhib for ACS
Prasugrel
Heparin is reversible with
Protamine
Initial drug therapy for Acute Pulmonary Embolism/ Venous Thromboembolic Disease
IV heparin or SQ enoxaparin, followed by transition to oral regimen (patient acutely ill or diagnosis doubted)
use of novel oral anticoagulants as initial therapy is reasonable (patients who are low risk)
In patients with ACUTE PE w/ hypotension and no bleeding risk, fibrinolytics are used (t-PA)
Long Term Drug Therapy for Venous Thromboembolic Disease
Novel oral anticoagulants for pts. w/o cancer
Pts. w/ cancer, enoxaparin
End stage renal disease, VKAs
Anti-Thrombotic Therapies and Indications
ACS initial therapy
anti-platelet + anti-coagulant
