anti hypertensive drugs

Question 1

A What are the names of the main ACE inhibiting drugs? end in pril

APRIL IS AN ACE MONTH

Also SARTAN - angiotensin receptor blockers

Answer 1

ace (angiotensin converting enzyme inhibitors) stop the vasoconstricting effect of angiotensin II on blood vessels. Stops the conversion of angiotensin 1 to angiotensin 2.

Captopril

side effects - cough/bronchospasm,

ALSO angiotensin receptor blockers - losartan, valsartan, canderstartan

again stop angiotensin II production.

Question 2

B BETA BLOCKERS - all end in LOL “LOL at betamax”

Answer 2

act on symathetic nervous system. take several weeks. reduce adrenaline, reduce cardio output and renin by kidney. tablets, BLOCK B1 receptors in heart.

Question 3

C - calcium channel blockers - end in pine

Answer 3

Nifedipine, Amlodipine, Nicardipine. (end in pine).

side effects - mild - hyperkalaemia

Question 4

D - diuretics LOOP (mainly end in IDE)

Answer 4

act on loop of henle. Severe hypertension, short duration,

flurosemide

side effects - increaces uric acid in blood plasma. HYPOCALAEMIA

Question 5

D - Diuretics THIAZINE like (mainly end in IDE)

Answer 5

1st line treatment.

Increase urine output. Bendroflumethiazide - stops sodium reabsorption.

Question 6

D Diuretcs - spiralactone/ amiloride

Answer 6

These are potassium sparing diuretcs. aldosterone antagonist. They should not be taken by anyone who has high levels of potassium in their blood, severe kidney problems, or Addison’s disease/kidney problems