Anti-coagulants

Question 1

Heparin

Onset:

Short-term/long-term:

Routes to give:

Labs to watch :

Antidote:

Can I give during pregnancy?

Will this medication breakdown a clot?

What is the potential complication of his drug therapy?

Answer 1

Onset: less than hour

Short-term/long-term: short term

Routes to give: IV or SQ
Nm
Labs to watch : PTT

Antidote:Protamine Sulfate

Can I give during pregnancy? Yes

Will this medication breakdown a clot? No

Heparin-induced Thrombocytopenia

Question 2

Coumadin

Onset:

Short-term/long-term:

Routes to give:

Labs to watch :

Antidote:

Can I give during pregnancy?

Will this medication breakdown a clot?

What is the potential complication of his drug therapy?

Answer 2

Onset: 4 to 10 day

Short-term/long-term: long-term

Routes to give: PO only

Labs to watch : INR or PT

Antidote: vitamin K

Can I give during pregnancy? No

Will this medication breakdown a clot? No

Coumadin induce necrosis

Question 3

Enoxaparin

Indication

Route

Patient Assessment

Contraindications

ReMar Notes

Answer 3

Indication-to prevent deep vein Thrombosis (DVT)

Route -subcutaneous injections or IV (less common(

Patient Assessment —-

1. medication should be clear with no particles or discoloration before injecting
2. Monitor for signs of bleeding

Contraindications -

1. do not give a patient has history of heparin induced thrombocytopenia.
2. Stop 24 hours before surgery
3. Not take with other blood thinners

ReMar Notes

1. This is considered a low molecule weight heparin (LMWH)

The benefits of of LMWH over heparin

1. Once daily injections
2. No lab monitoring
3. Can be prescribed as outpatient therapy