Anterior Pituitary Flashcards

1
Q

Which hormones are secreted by the anterior pituitary

A

TSH, GH, LH, FSH, Prolactin, ACTH

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2
Q

The hypothalamus is linked to the anterior pituitary by

A

The hypothalamohypophyseal portal system

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3
Q

The hypothalamus is linked to the posterior pituitary by

A

The hypothalamohyphophyseal tract

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4
Q

Function of parvicellular neurons

A

secrete releasing or inhibiting neurohormones

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5
Q

Which hormone is usually under inhibition by the hypothalamus

A

Prolactin

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6
Q

Which hormone inhibits prolactin

A

dopamine

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7
Q

Which hormone stimulates secretion of prolactin

A

TRH

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8
Q

Which hormone inhibits GH secretion

A

Somatostatin

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9
Q

GH acts on which peripheral tissue

A

The liver

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10
Q

Which hormones are proopiomelanocortin

A

ACTH and MSH

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11
Q

In which nuclei is TSH synthesized

A

Paraventricular nuclei

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12
Q

What are the taget cells for gonadotropins in females

A

Granulosa and thecal cells

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13
Q

What are the taget cells for gonadotropins in males

A

Sertoli and Leydig cells

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14
Q

Fast GnRH pulses causes release of which hormone

A

LH

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15
Q

Slow GnRH pulses causes release of which hormone

A

FSH

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16
Q

ACTH has high affinity for which receptors in the adrenal cortex

17
Q

What is the role of ACTH in the adrenal cortex

A

steroidogenesis and cell growth of the cortex

18
Q

Which receptor is responsible to activate MSH

19
Q

Disruption of the pituitary stalk or the hypothalamohypophyseal portal vessels causes levels of all tropic hormones to decrease except ______

20
Q

Apart from dopamine, which other substances can inhibit prolactin secretion

A

Somatostatin, TSH, γ-aminobutyric acid (GABA) and GH

21
Q

Prolactin inhibits release of which hormone

22
Q

Which two substances can inhibit GnRH release

A

Beta endorphin and prolactin release

23
Q

Which condition can inhibit GH secretion

24
Q

Which conditions can stimulate GH secretion

A

Arginine, exercise and starvation

25
Four main effects of GH secretion
increased lipolysis, increased protein synthesis, increased gluconeogenic enzymes, decreased glucose uptake
26
GH favors which kind of bone growth before and after puberty
longitudinal bone growth before puberty, circumferential bone growth after puberty
27
GH is transported in serum by which protein to affect bone growth?
It is transported by IGFBP-3
28
GH stimulates hepatic production of which three molecules to increase bone growth
IGF-I, IGFBP-3, and ALS