ANI SCI 320 Lecture 6 : Biofilms Flashcards
What are biofilms?
Highly structured microbial communities enmeshed in a self produced slime matrix of proteins, polysaccharides, eDNA, and lipids
TRUE or FALSE? Biofilms are highly complex?
TRUE
Stringy biofilms only contain….
eDNA
Chunky biofilms only contain…..
proteins
Webby biofilms contain…..
EVERYTHING
What are the 5 biofilm development stages?
- Colonization/adhesion
- Aggregation
- Microcolony/monolayer formation
- Maturation
- Dispersal
Non specific attachment ways include?
- Physio-chemical
- Pili-mediated
- Flagella-mediated
Specific attachment ways include?
- Receptor Mediated
- Host ECM components
Biofilms are predominantly…..
polymicrobial
Multiorganism communities include?
- Bacterial Fungal Biofilms
- Bacterial Algal Biofilms
TRUE or FALSE? Increasing bacterial diversity increases survivial?
TRUE
How do antimicrobial and antibiotics develop resistance?
Develop mutations that render the antibiotic/toxin ineffective due to intrinsic or acquired resistance
What is intrinsic resistnace?
Inherited physiological property
What is acquired resistance?
Mutations and gene acquistion
What is tolerance?
Ability to survive transient exposure to a high concentration of an antibiotic despite being susceptible/
