Alzheimers

Question 1

Donepezil

Answer 1

First-line
5mg orally at night for 4 weeks.
Mild - moderate
Side effects: bradycardia, heart block, seizure, agitation, hallucination, confusion

Question 2

Galantamine MR

Answer 2

First-line
8mg orally in morning
Mild-moderate
Side effects: bradycardia, heart block, seizure, agitation hallucination.

Question 3

Rivastigmine patch

Answer 3

First Line
4.6mg transdermal
Mild to moderate
Side Effects: mainly skin reaction at application site.

Question 4

Rivastigmine tablet

Answer 4

Second-line
1.5mg orally
Mild-moderate
Side Effects: bradycardia, heart block, seizure, agitation, hallucination

Question 5

Memantine

Answer 5

First line
Moderate-severe Alzheimer’s
5mg initially then increase to 20mg over a few weeks
Side effects: confusion, dizziness, drowsiness, headache, insomnia, agitation, hallucination, dyspnoea, hypersensitivity