Aerobic Metabolism Flashcards
Long term energy system
Aerobic metabolism
Aerobic metabolism gets energy from
CHO, Proteins, Fats
Pyruvate moves into the mitochondria through
Protein channel- monocarboxylase transporter 1 (MCT1)
2 possible shuttles for NADH H+
1) Malate aspartate
2 )Glycerol Phosphate
The conversion of pyruvate into acetyl coA
Pyruvate + Coenzyme A + NAD+
↓ enzyme: Pyruvate dehydrogenase
Acetyl CoA
CO2
NADH H+
Krebs Cycle (Citric Acid Cycle) occurs in the
mitochondrial matrix
Krebs Cycle Steps
Rate limiting enzyme for Krebs Cycle
Isocitrate dehydrogenase
1 Acetyl CoA generates
1 ATP
2 CO2
1 FADH2
3 NADH H+
The ETC: NADH H+ pathway
Complex I
↓
Coenzyme Q
↓
Complex III
↓
Cytochrome C
↓
Complex IV
ETC: FADH2 pathway
Complex II
↓
Coenzyme Q
↓
Complex III
↓
Cytochrome C
↓
Complex IV
ETC: the ATPase
once a concentration gradient is created in the intermembrane space (14 hydrogen), H+ will flow back into the matrix
Allows ADP + Pi
↓
ATP
Which molecule produces less ATP
FADH2 OR NADH H+
FADH2
- because complex 2 does not pump H+
Role of Electrons in the ETC
Transported through the protein complexes to combine with O2 and H+ (H20 @ Complex IV)
of ATP Produced through ETC/ 1 glucose
30-32