Adrenal Physiology Flashcards

1
Q

List the parts of the adrenal gland

A

Outer Capsule
Cortex
Medulla

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2
Q

What are the 3 zones located in the adrenal cortex?

A

Zona glomerulosa
Zona fasciculata
Zona reticularis

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3
Q

Which cells are located in the adrenal medulla?

A

Chromaffin cells

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4
Q

What controls hormonal release in the zona glomerulosa?

A

RAAS (angiotensin II)

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5
Q

Which hormone is secreted from the zona glomerulosa?

A

Aldosterone

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6
Q

What controls hormonal release in the zona fasciculata?

A

ACTH

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7
Q

What hormones are secreted from the zona fasciculata?

A

Cortisol

Corticosterone

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8
Q

What controls hormonal release in the zona reticularis?

A

ACTH

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9
Q

What hormones are secreted from the zona reticularis?

A

Androgens (sex hormones)

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10
Q

What controls hormonal release in the adrenal medulla?

A

Sympathetic nervous system

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11
Q

What hormones are secreted from the adrenal medulla?

A

Catecholamines (adrenaline, noradrenaline)

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12
Q

Outline the hypothalamus-pituitary-adrenal cortex axis

A

HYPOTHALAMUS secretes CRH which stimulates anterior PITUITARY to secrete ACTH which stimulates the ADRENAL GLAND to secrete cortisol

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13
Q

Which parts of the H-P-adrenal cortex axis does cortisol inhibit in negative feedback?

A

Hypothalamus

Anterior pituitary

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14
Q

Which system regulates aldosterone release?

A

RAAS

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15
Q

What is the effect of cortisol upon the CNS?

A

Varying mood
Psychosis
Loss of libido

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16
Q

What is the effect of cortisol upon bone?

A

Osteoporosis

17
Q

What is the effect of cortisol upon metabolism?

A

Increases breakdown of carb, lipid and protein

18
Q

What are the main effects of aldosterone?

A

Increased K + H ion excretion

Sodium retention