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ADR Flashcards

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1
Q

ADR of Benzodiazepines

A
  • Sedation
  • Muscle weakness
  • Ataxia
  • Amnesia

Rare:
- Slurred speech
- Headache
- Confusion
- Paradoxical excitement

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2
Q

ADR of Z-hypnotics

A
  • Taste disturbance (zopiclone)
  • Dry mouth
  • N&V
  • Dizziness
  • Drowsiness
  • Headache

Less common:
- Amnesia
- Confusion
- Hallucinations
- Complex sleep behaviours

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3
Q

ADR of circadin

A

Headache

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4
Q

ADR of lemborexant

A
  • Somnolence
  • Nightmare

Less common:
- Sleep paralysis
- Hypnagogic / hyponopomic hallucinations
- Cataplexy-like symptoms

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5
Q

ADR of levodopa

A

Short-term:
- Nausea, vomiting
- Orthostatic hypotension
- Drowsiness, sudden sleep onset

Long-term:
- Hallucinations, psychosis
- Dyskinesia

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6
Q

ADR of COMT inhibitors

A
  • Diarrhea
  • Urine discolouration
  • Worsened dyskinesia, orthostasis, nausea from levodopa
  • Liver dysfunction (tolcapone)

Rare:
- Visual hallucinations
- Daytime drowsiness, sleep disturbances

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7
Q

ADR of MAO-b inhibitors

A
  • Heartburn, anorexia
  • Anxiety, palpitations
  • Insomnia, nightmares
  • Visual hallucinations
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8
Q

ADR of dopamine agonists

A

Short-term:
- Nausea, vomiting
- Orthostatic hypotension
- Drowsiness, sudden sleep onset

Long-term:
- Hallucinations, psychosis
- Dyskinesia

+ Psychosis, leg edema
More orthostasis, sleep disturbance, compulsive behaviours

Ergot-related
- Fibrosis
- Cardiac valve regurgitation

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9
Q

ADR of amantadine

A
  • Nausea
  • Dizziness
  • Cognitive impairment (difficulty concentrating)
  • Hallucinations
  • Insomnia, nightmares
  • Livedo reticularis
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10
Q

ADR of trihexyphenidyl

A
  • Dry mouth
  • Sedation
  • Constipation
  • Urinary retention
  • Delirium, confusion
  • Hallucinations
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11
Q

ADR of cholinesterase inhibitors

A
  • Cholinergic (nausea, vomiting, diarrhea)

Less common:
- Anorexia
- Increased gastric acid secretion
- Vivid dreams, insomnia
- Muscle cramps
- Bradycardia (C/I)

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12
Q

ADR of lithium

A
  • Acne
  • Tremors
  • Polyuria, diabetes insipidus
  • Hypothyroidism
  • ECG changes
  • Nausea
  • Weight gain
  • Fatigue
  • Cognitive impairment
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13
Q

ADR of memantine

A
  • Headache
  • Confusion
  • Dizziness
  • Hallucination
  • Constipation
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14
Q

Cautions for acetylcholinesterase inhibitors

A
  • Peptic ulcer disease
  • Respiratory disease
  • Seizure disorder
  • Urinary obstructin

Contraindicated in bradycardia

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15
Q

Cautions for memantine

A
  • CVD
  • Seizure disorder
  • Severe hepatic/renal impairment
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Psych (5 decks)

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