additional thoughts Flashcards

1
Q

The human genome has about how many genes?

A

20 000

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2
Q

What are genetic polymorphisms?

A

sites in the genome that vary among different individuals, and usually refers to a genetic variant that occurs in 1% of the population

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3
Q

What is the exome?

A

portion of the genome that codes for protiens

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4
Q

Chromosomes consist of 2

A

-chromatin and histones

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5
Q

Epigenetic inheritance depends on ____

A

factors other than DNA

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6
Q

An epigenetic state can usually be ____

A

reversed

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7
Q

Interchromosomal interactions can be shown through ___ treatment

A

hormone

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8
Q

What is a topologically associated domain?

A

TAD - regions in a genome where DNA in that region interacts more strongly with other DNA in that region

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9
Q

RNA polymerase moves in the ________ direction

A

3-5

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10
Q

General transcription factors assemble at the _____ just upstream of the transcriptional start site to recruit and modify _____

A

pre initiation complex, RNA pol II

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11
Q

does peptide bond formation require energy?

A

no, spontaneous

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12
Q

RNA interference has potential for treating what?

A

Huntingtons

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13
Q

What is bromodeoxyuridine?

A

BrdU - thymidine analog that incorporates DNA of dividing cells

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14
Q

What is the main DNA polymerase in prokaryotes?

A

Pol III

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15
Q

DNA replication takes place in what phase of the cell cycle?

A

S

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16
Q
A