Action potential part 2 Flashcards

To learn about action potentials

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1
Q

What are action potentials?

A

Process by which an electrical impulse is generated, driven by changes in voltage across the membrane of the neuron.

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2
Q

What makes a neuron fire?

A

When dendrites receive input/signal from another neuron

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3
Q

In order for an action potential to occur there needs to be a disturbance with the ___________________

A

Resting potential

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4
Q

Membrane potential is more positive than it was at resting membrane potential.

Make it more positive / less negative

A

Depolarization

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5
Q

Membrane potential is more negative than it was at resting membrane potential.

A

Hyper-polarization

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6
Q

In order to understand what happens to the cell during the resting potential we must understand what is happening inside and outside of the _______________

A

Membrane

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7
Q

Intracellular fluid is called ___________

A

Cytosol

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8
Q

Extracellular fluid is called ___________

A

Interstitial

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9
Q

The membrane potential is

A

The charge of the cell at rest. (When there’s no stimulation going on)

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10
Q

Typically the membrane potential is between

A

-65 to -75 m

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11
Q

Why is the charge negative on membrane potential?

A

Because we have a constant influx and efflux of ions in and out of the cell at rest even when the cell is not being stimulated

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12
Q

They key ions of the maintenance of the membrane potentials are

A

K+= Potassium
NA = Sodium

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13
Q

If the resting membrane potential is negative or if the charge inside of the cell is less than the charge outside of the cell we must know that we are losing more positive ions than we’re gaining into the cell in order for that charge to be negative

A
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14
Q

Sodium & Potassium plays a role in this type of polarization of ions

A

Depolorization

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15
Q

The sodium potassium pump’s jobs is to

A

maintain resting membrane potential and ensure that its negative

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16
Q

Potassium plays a role in the type of polarization of ions

A

Hyper-polorization

17
Q

All membranes have ion channels that allow specific ions to pass though . What are they?

A

1.Non-gated
2.Open-gated

18
Q

Define non-gated (open)

A

Channels that are always open and are not influenced significantly by extrinsic factors. They maintain the resting membrane potential.

19
Q

Define Gated (closed)

A

Channels open and close. In response to specific electrical, mechanical and chemical signals.

20
Q

Transient current flow and therefore rapid changes are made possible by

A

ion channels in the membrane

21
Q

The effects of the gates will supersede

A

Sodium and Potassium pumps

22
Q

If you have an electrical , mechanical signal it can trigger this gate to open or close

A

Gated

23
Q

Voltage gated channels

A

based on voltage or electrical signal

24
Q

Describe the process of the action potential:

A

1.Resting potential is stimulated by signal
2.Opening of voltage gated sodium channel to allow sodium to rush into the cell
3. De-polarization using sodium and potassium
4.Once you hit the threshold , all sodium channels open and cell will begin to rapidly polarize
4. Rapid depolarization is what sending the signal
5. Action potential peak
6.When we’ve gotten enough positive charge and after the peak, we resolve the signal by shutting voltage gates for sodium and open up potassium voltage gates instead
7.This causes re-polarization to occur.
8.The cell can go back to its rest state or it can be hyper-polarized
9.This occurs when the membrane potential is more negative than it was at rest.
10.Refractory period
11.Sodium and Potassium pumps bring it back to mrp -70mv

25
Q

What is the threshold for positive ions in an action potential voltage?

A

-55 mv

26
Q

What is the threshold in the process of the action potential?

A

the point that the action potential occurs

27
Q

What needs to occur for an action potential to happen ?

A

The threshold needs to be hit and depolarization happens

28
Q

Moderate or strong signals will hit the

A

Threshold

29
Q

Week signals do not

A

Generate action potentials and are failed initiatives

30
Q

All or none principal means

A

If neuron is sufficiently stimulated it fires, sending the action potential down to the axon and releasing chemicals. The action occurs or it doesn’t

31
Q

Refractory period refers to the

A

function of hyper polarization when the membrane potential is below the resting state

32
Q

0 Excitability happens during the _______________ because there’s no chance that the nerve cells are going to fire.

A

Absolute refractory period

33
Q

What are the 2 types of refractory periods?

A

Absolute and Relative

34
Q

Excitability increases during the _______________ period meaning we’ll be able to generate another action potential because we are closer to resting membrane potential.

A

Relative refractory period

35
Q

The further you are from the threshold is the harder it will be to generate an action potential.

What principal is that

A

All or nothing

36
Q

All or nothing principal govern the ________ period

A

refractory period

37
Q

Where are the voltage-gated ion channels located in the cell?

A

Great job! The voltage-gated ion channels are located at the axon hillock and along the axon

38
Q

True or False ?

The presence of myelin insulates the axon, which increases action potential speed

A

True

39
Q
A