8. Selective serotonin and/or norepinephrine reuptake inhibitors. Flashcards

1
Q

Selective serotonin reuptake inhibitors (SSRI)

A

first line of action antidepressants
take 1 to 2 months to achieve maximal effect

drugs...
Fluoxetine 
Paroxetine 
Sertraline 
Citalopram
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2
Q

Selective serotonin & norepinephrine reuptake inhibitors (SSNRI)

A

for patients not responding to SSRIs and chronic painful symptoms
take 1 to 2 months to achieve maximal effect

drugs…
Duloxetine
Milnacipran
Levomilnacipran

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3
Q

Selective norepinephrine reuptake inhibitors (SNRI)

A

Reboxetine

Atomoxetine

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4
Q

Fluoxetine

A

should be discontinued for 6 weeks before MAOI treatment is initiated
for bulimia nervosa
lowest risk for discontinuation syndrome
long half-life

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5
Q

Paroxetine & Sertraline

A

short acting

discontinuation syndrome

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6
Q

Duloxetine

A

Urinary stress incontinence

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7
Q

Milnacipran

A

for patients not responding to SSRIs and chronic painful symptoms
used for fibromyalgia as well

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8
Q

discontinuation syndrome

A

withdrawal syndrome

flu-like symptoms, trouble sleeping, nausea, poor balance, sensory changes, and anxiety

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