8. Selective serotonin and/or norepinephrine reuptake inhibitors. Flashcards
Selective serotonin reuptake inhibitors (SSRI)
first line of action antidepressants
take 1 to 2 months to achieve maximal effect
drugs... Fluoxetine Paroxetine Sertraline Citalopram
Selective serotonin & norepinephrine reuptake inhibitors (SSNRI)
for patients not responding to SSRIs and chronic painful symptoms
take 1 to 2 months to achieve maximal effect
drugs…
Duloxetine
Milnacipran
Levomilnacipran
Selective norepinephrine reuptake inhibitors (SNRI)
Reboxetine
Atomoxetine
Fluoxetine
should be discontinued for 6 weeks before MAOI treatment is initiated
for bulimia nervosa
lowest risk for discontinuation syndrome
long half-life
Paroxetine & Sertraline
short acting
discontinuation syndrome
Duloxetine
Urinary stress incontinence
Milnacipran
for patients not responding to SSRIs and chronic painful symptoms
used for fibromyalgia as well
discontinuation syndrome
withdrawal syndrome
flu-like symptoms, trouble sleeping, nausea, poor balance, sensory changes, and anxiety