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Question 1

Cause of trichinellosis infection?

Answer 1

Eat raw/undercooked meat

-esp. pork

Question 2

What is special about trichinella larvae and worms?

Answer 2

develop in same host

Question 3

Life Cycle of Trichinella

Answer 3

Ingest larvae & released into SI
Enter mucosa & mature in 48 hrs to worm
Worm lives 4-6wks & females release larvae
Larvae enter circulation & migrate to ACTIVE skeletal muscle
Larvae in muscle viable for mo - yrs

Question 4

Clinical Manifestations of Intestinal Phase of Trichinellosis

Answer 4

N/V/D, abd pain

Begin 1-2days post infection & abate 2-5wks later

Question 5

Clinical Manifestations of Systemic Phase of Trichinellosis

Answer 5

Myalgia, facial swelling, eosinophilia, subungal splinter hemorrhages, constitutional
Begin within 2wks post inf & last >8wks

Question 6

Complication of heavy infection of Trichinellosis

Answer 6

Life threatening heart, CNS, lung, kidney damage

Question 7

Humans are what type of host in Larva Migrans?

Answer 7

Accidental!

Question 8

Presumed Diagnosis of Trichinellosis

Answer 8

Periorbital Edema, Eosinophila, Hx of eating raw/undercooked meat

Question 9

Larva migrans infection?

Answer 9

Accidental ingestion of egg or larvae, larvae migrate through tissues, but do not mature into adult worm. Immune response of host contributes to pathology

Question 10

Causative Agents of Visceral Larva Migrans

Answer 10

Toxocara canis (d0g)
Toxocara cati (cat)

Question 11

Visceral Larva Migrans most commonly infects?

Answer 11

Children who play in soil contaminated with dog or cat feces

Question 12

S&S of VLM are result of?

Answer 12

Migrating larvae and host eosinophilic granulomatous response

Question 13

TRX of Trichinellosis

Answer 13

Albendazole or Melbendazole

Question 14

TRX of Larva Migrans

Answer 14

Albendazle or Melbendazole

Question 15

Causative agents of Cutaneous Larva Migrans

Answer 15

Ancylostoma braziliense

Ancylostoma caninum

Question 16

S&S of CLM

Answer 16

Intially: pruritic red papules at penetration sites
2/3days later: pruritic, elevated, serpiginous, red-brown lesions

Usually resolve in 2-8wks