5.4 - Malaria treatment Flashcards
Falciparum malaria first line treatment
Artemisinin + Lumefantrine
Falciparum malaria alternative treatment
Oral Quinin OR Atovaquone with proguanil
Treatment for severe/complicated falciparum malaria
IV Artesunate
Alternative Treatment for severe/complicated falciparum malaria
- Oral quinine with (doxycycline or clindamycin)
- Atovaquone with proguanil HCL
Treatment for uncomplicated falciparum malaria in 2nd/3rd trimester
Artemether with lumefantrine
Treatment for uncomplicated falciparum malaria in all trimester
Quinine with clindamycin
1st line treatment for severe/complicated falciparum malaria
IV Artesunate
Alternative treatment for severe/complicated falciparum malaria
IV quinine with clindamycin
What is the risk of using quinine in pts who are pregnant?
- Increased risk of uterine contractions
- Hypoglycaemia
Non falciparum malaria is caused by what organisms?
- Plasmodium vivax
- P. Ovule
- P. malaria
- P. Knowles
What is the 1st line treatment of non falciparum malaria?
Artemether with lumefantrine
OR
Chloroquine
Which antimalaria specific targets –> P. malaria & P. Knowles
Chloroquine
Which antimalaria [radical cure] specific targets –> P. malaria & P. Knowles
Primaquine
What are two cautions when giving Primaquine
- Postponed until pregnancy due to baby not being G6PD NORMAL
- Screened for G6PD deficiency as may cause haemolysis
What is the 1st line treatment of severe/complicated non falciparum malaria?
Parenteral artesunate or Quinine
What is the treatment of non falciparum malaria in pregnacy?
Chloroquine
OR
Artemisinin combination - 2nd/3rd trimester
OR
P.vivax chloroquine resistant = Quinine
