5. Membranes As Permeability Barriers Flashcards
What are the roles of the transport process?
Maintenance of ionic composition
Maintenance of intracellular pH
Regulation of cell volume
What is the PMCA?
Plasma membrane Ca2+ ATPase
Primary active transporter
Uses ATP, converts to ADP
Transports Ca2+ from inside to outside of cell
What is co-transport?
More than one type of ion or molecule may be transported on membrane transporter per reaction cycle
What is a uniport?
One ion/molecule transported
What is a symport?
Ion/molecule an co-transported ion/molecule both travel in same direction through protein
What is an antiport?
Transported ion/molecule and co-transported ion/molecule travel in opposite directions through protein
Describe the Na+/K+ ATPase (sodium pump) process
3 Na+ transported out for every 2 K+ transported in
High conc of sodium outside cell, high conc of potassium inside cell
Uses ATP
What is the role ofCa2+ - Mg2+ - ATPase pump?
Pumps Ca2+ out of cell
High affinity
Transports when not much calcium in cell
Low capacity
What is the role of Na+ - Ca2+ exchanger?
Pumps 1 calcium out of cell for every 3 sodium into cell Low affinity Transports when high conc of calcium High capacity Antiport
What is the role of Na+ - H+ exchanger?
Pumps 3 sodium out for every 2 potassium in, using ATP
One sodium in for every hydrogen out