3.8 Flashcards
What are the components of a nucleotide?
Pentose monosaccharide
Phosphate group
Nitrogenous base
How are nucleotides linked together
Condensation reaction. Phosphate group on 5th carbon of sugar forms covalent bond w hydroxyl group on 3rd carbon of other nucleotide. Called phosphodiester bonds. Forms a sugar phosphate backbone.
How are phosphodiester bonds broken
Hydrolysis
What are the four bases in DNA
Adenine
Thymine
Guanine
Cytosine
What are the smaller bases called and what bases are they?
Pyrimidines
Thymine cytosine
What are the larger bases called and what bases are they?
Purines
Adenine guanine
Differences between DNA and rna
Deoxyribose sugar DNA has thymine base Rna Ribose sugar Uracil base
What shape has DNA got and how?
Two strands of polynucleotides wound together in a double helix (antiparallel) held together by hydrogen bonds between bases.
Base pairing rules
Adenine and thymine able to form 2 H bonds so only bind w each other
Cytosine and guanine able to form 3 H bonds so only bind w each other
Pyrimidine always binds w purine
Equal amounts of adenine and thymine and equal amounts of guanine and cytosine