265 Mitral Valve Prolapse Flashcards
Other names for MVP (4)
most common abnormality leading to primary mitral regurgitation (MR)
MVP
A reduction in the production of WHAT TYPE of collagen has been implicated, and electron microscopy has revealed fragmentation of collagen fibrils in MVP
Type III collagen
MVP is a frequent finding in patients with heritable disorders of connective tissue, including (3)
Marfan syndrome
osteogenesis imperfecta,
Ehlers-Danlos syndrome
In most patients with MVP, myxomatous degeneration is confined to WHAT VALVE
MITRAL VALVE
In MVP, which mitral leaflet is more affected…. posterior or anterior?
Posterior
MVP is more common in women than men. True or False
True
most frequently between the ages of ____ and ____ years
most frequently between the ages of 15 and 30 years;
There is an increased familial incidence for some patients, suggesting what form of inheritance and penetrance?
There is an increased familial incidence for some patients, suggesting an autosomal dominant form of inheritance with incomplete penetrance.
most common cause of isolated severe MR requiring surgical treatment.
MVP
defined as abnormal atrial displacement of the mitral valve leaflet hinge point
mitral annular disjunction
Character of chest pain associated with MVP (3)
substernal, prolonged, and not related to exertion
frequent auscultatory finding in MVP
mid- or late (nonejection) systolic click
Reason for the systolic click in MVP (2)
Systolic clicks in MVP may be multiple and may be followed by what type of murmur (include characteristics )
a high-pitched, mid-late systolic crescendo–decrescendo murmur
Quality of sound used to describe the murmur following the systolic click of MVP (2)
“whooping” or “honking”
Systolic clicks in MVP be multiple and may be followed by this type of murmur that is best heart at what part of the heart
apex
q
Differentiate the murmurs anterior and posterior leaflet prolapse in MVP in terms of (1) direction of jet of MR and (2) location of radiation
The MVP click and murmur occur at what phase of the Valsalva maneuver
Strain phase
Effect of squatting in MVP
diminish MVP
Effect of isometric exercises in MVP
diminish MVP
most common ECG finding in MVP
normal
useful echocardiographic definition of MVP
systolic displacement (in the parasternal long axis view) of the belly of the mitral valve leaflets by at least 2 mm into the left atrium (LA) superior to the plane of the mitral annulus.
the jet lesion of MR due to MVP
is most often eccentric. True or False
True
